Author

Z. Ying

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Physiology· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:proteomics· 3

Frequent Co-Authors

Y. Zhang· 3 shared J. Liu· 2 shared S. Kooijman· 2 shared Y. Chen· 2 shared Y. Wang· 2 shared A. Binnendijk· 1 shared A. C. M. Pronk· 1 shared A. Kovynev· 1 shared

Activity by Year

2019-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersAnimal Behavior & Cognition

Y. Zhang

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Toxoplasma gondii infection alters the recognition response of dendritic cells to stiffness substrate: A new model of cell durotaxis migration

Q. Liu, Z. Sun, J. Liu, Z. Zhu, Z. Ying, Z. Zhou

This paper shows that Toxoplasma gondii infection changes dendritic cell durotaxis by altering F-actin structure and FAK phosphorylation, promoting parasite brain dissemination.

bioRxiv · Mar 31, 2023 · PreprintPathology

Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia

Z. Ying, S. Hardikar, J. B. Plummer, T. Hamidi, B. Liu, Y. Chen, J. Shen, Y. Mu, K. M. McBride, T. Chen

This study characterizes a mouse model of ICF syndrome, revealing that Zbtb24 deficiency leads to hypogammaglobulinemia via enhanced CD19 activation and IL-5 signaling.

bioRxiv · Mar 9, 2023Immunology

Time to run: Late rather than early exercise training in mice remodels the gut microbiome and reduces atherosclerosis development

M. Schonke, Z. Ying, A. Kovynev, W. In het Panhuis, A. Binnendijk, S. van der Poel, A. C. M. Pronk, T. C. M. Streefland, M. Hoekstra, S. Kooijman, P. C. N. Rensen

This study shows that late exercise training in mice reduces atherosclerosis and alters gut microbiota composition, while early exercise does not produce similar benefits.

bioRxiv · Nov 28, 2022Physiology

Spatial Localization Ability of Planarians Identified Through the Light Maze Paradigm

R. Qian, Y. Yan, Y. Zhang, Y. Chi, Y. Chen, K. Hao, Z. Xu, G. Yang, Z. Shao, Y. Wang, X. Li, C. Lu, K. Chen, Y. Pei, W. Zhang, , K. Huang

This paper demonstrates that planarians can navigate to a previously recognized location in a new maze, indicating they have spatial localization ability.

bioRxiv · Nov 17, 2022Animal Behavior & Cognition

Proliferative Exhausted CD8 T Cells Exacerbate Long-lasting Anti-tumor Effects in Human Papillomavirus Positive Head and Neck Squamous Cell Carcinoma

D. Cheng, K. Qiu, Y. Rao, M. Mao, L. Li, Y. Wang, Y. Song, J. Chen, X. Yi, X. Shao, S. H. Huang, Y. Zhang, X. Chen, S. Wu, S. Yu, , J. Ren

The paper identifies a proliferative exhausted CD8+ T cell cluster in HPV-positive HNSCC that correlates with better patient survival and suggests potential therapeutic implications.

bioRxiv · Oct 27, 2022Immunology

Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: a randomized cross-over trial

M. Straat, L. Jurado Fasoli, Z. Ying, K. J. Nahon, L. Janssen, M. Boon, G. Grabner, S. Kooijman, R. Zimmermann, M. Giera, P. C. Rensen, B. Martinez

This study shows cold exposure increases circulating free fatty acids and transiently lowers total triacylglycerols in humans, with dynamic changes in TAG species dependent on saturation and chain length, and this effect is mediated by intracellular lipolysis.

bioRxiv · Sep 9, 2022Physiology

Encoding sensing functions into material interface for a rationally engineered integrated electrochemical liquid biopsy

Y. Zhang, H. Zhu, Z. Ying, X. Gao, W. Chen, Y. Zhan, L. Feng, C.-c. Liu, Y. Dai

This paper develops an integrated electrochemical liquid biopsy platform for detecting cancer exosomes from blood using a rational engineering strategy.

bioRxiv · Jan 17, 2022 · PreprintBioengineering

SOX2-phosphorylation toggles a bistable differentiation-switch in squamous cell carcinoma

S. Hoang-Phou, A. Sastre-Perona, M. Abbruzzese, Z. Ying, J. Siegle, B. Aranda Orgilles, P. P. Rocha, I. Aifantis, J. Skok, S. Beronja, M. Schober

This paper identifies a mechanism by which SOX2-phosphorylation toggles a bistable differentiation switch in squamous cell carcinoma, enabling tumor-propagating cells to transition from self-renewal to differentiation.

bioRxiv · Aug 18, 2021 · PreprintCancer Biology

TP63, SOX2 and KLF5 Establish Core Regulatory Circuitry and Construct Cancer Specific Epigenome in Esophageal Squamous Cell Carcinoma

Y. Jiang, Y. Jiang, C.-Q. Li, Z. Ying, P. Dakle, J.-W. Deng, R. Y.-T. Lin, H. Kaur, L. Han, J.-J. Xie, A. Mayakonda, M. Hazawa, L. Xu, Y. Li, L. Aswad, , H. P. Koeffler

This study identifies TP63, SOX2, and KLF5 as core regulatory circuitry transcription factors in ESCC that drive epigenetic modifications and tumor growth through super-enhancer interactions.

bioRxiv · Nov 6, 2019 · PreprintCancer Biology