Author

W. Hao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

X. Wang· 3 shared B. Qin· 2 shared D. Wang· 2 shared J. Han· 2 shared J. Sun· 2 shared K. He· 2 shared L. Wang· 2 shared S. Cui· 2 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersPaleontology

X. Wang

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Basal Cambrian soft-bodied segmented bilaterians preserved as microbial pseudomorphs

X. Yang, D. Wang, Z. Zhang, X. Wang, J. Sun, W. Hao, Y. Liu, K. Uesugi, T. Komiya, J. Han

This study identifies microbial pseudomorphs as the earliest three-dimensional body fossils of segmented bilaterians from the basal Cambrian, revealing a diversified bilaterian world.

bioRxiv · Jul 3, 2024 · PreprintPaleontology

Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis

L. Wu, J. Chen, Y. Wu, W. Hao, J. You

This study identifies hepatic androgen receptor as a mediator of glucagon sensitivity in female mice, revealing its role in glucose and lipid metabolism via the PGC1α/ERRα/mitochondria axis.

bioRxiv · Nov 2, 2023Physiology

Dynamic simulations of feeding and respiration of the early Cambrian periderm-bearing cnidarian polyps

Y. Zhang, X. Wang, J. Han, J. Xiao, Y. Yong, C. Yu, N. Yue, J. Sun, K. He, W. Hao, T. Zhang, B. Wang, D. Wang, X. Yang

This study simulates the feeding and respiration of early Cambrian cnidarian polyps using CFD to show how muscle contractions drive water flow, supporting hypotheses about ancestral medusozoan behavior.

bioRxiv · Jul 28, 2023Evolutionary Biology

Single-cell transcriptomic analyses reveal the cellular and genetic basis of aquatic locomotion in scyphozoan jellyfish

Y. Li, S. Peng, Y. Liu, K. He, K. Sun, Z. Yu, Y. Ma, F. Wang, P. Xu, T. Sun, H. Zheng, L. Ye, L. Wang, W. Hao, J. Zhao, , Z. Dong

The paper was withdrawn due to the need for additional experimental evidence and reorganization of data and writing.

bioRxiv · Feb 6, 2023 · PreprintEcology

Nuclear soluble cGAS senses DNA virus infection

Y. Wu, K. Song, W. Hao, L. Wang, S. Li

This study shows HSV-1 infection releases cGAS from chromatin into the nucleus, where it senses viral DNA and activates type I IFN production.

bioRxiv · Aug 27, 2021 · PreprintImmunology

Data driven mathematical model of colon cancer progression

A. Kirshtein, S. Akbarinejad, W. Hao, T. Le, R. A. Aronow, L. Shahriyari

This study develops a data-driven mathematical model to analyze immune microenvironment interactions in colon cancer, revealing varying effects of macrophage activation on tumor progression across patient groups.

bioRxiv · Nov 2, 2020Cancer Biology

Mechanism of duplex unwinding by coronavirus nsp13 helicases

X. Hu, W. Hao, B. Qin, Z. Tian, Z. Li, P. Hou, R. Zhao, S. Cui, J. Diao

This paper investigates the unwinding mechanism of coronavirus nsp13 helicases using single-molecule FRET, revealing distinct step sizes and NTP hydrolysis patterns between MERS-CoV and SARS-CoV-2 nsp13.

bioRxiv · Aug 2, 2020 · PreprintBiophysics

Binding of the SARS-CoV-2 Spike Protein to Glycans

W. Hao, B. Ma, Z. Li, X. Wang, X. Gao, Y. Li, B. Qin, S. Shang, S. Cui, Z. Tan

This study compares the binding of SARS-CoV-2, SARS-CoV, and MERS-CoV spike proteins to glycans, finding HS binding is sulfation-dependent and sialic acid binding is absent.

bioRxiv · May 17, 2020Biochemistry

Identifying Priority Landscapes for Conservation of Snow Leopards in Pakistan

S. Hameed, J. u. Din, H. Ali, M. Kabir, M. Younas, W. Hao, R. Bischof, M. A. Nawaz

This study identifies priority landscapes for snow leopard conservation in Pakistan using species distribution modeling and connectivity analysis.

bioRxiv · Jan 27, 2020Zoology

Fin whale (Balaenoptera physalus) mitogenomics: A cautionary tale of defining sub-species from mitochondrial sequence monophyly

A. A. Cabrera, J. P. A. Hoekendijk, A. Aguilar, S. G. Barco, S. Berrow, D. Bloch, A. Borrell, H. A. Cunha, L. Dalla Rosa, C. P. Dias, P. Gauffier, W. Hao, S. Landry, F. Larsen, V. Martin, , M. Berube

This paper reanalyzes fin whale mitogenomic data and finds that apparent monophyly used to define subspecies is due to low sampling, not true genetic separation.

bioRxiv · Dec 6, 2018Evolutionary Biology