Y. Lu

The paper identifies a circadian mechanism regulating collagen synthesis, assembly, and degradation to maintain tissue homeostasis in mice.

The Tcb1-female gene encodes a Pectin Methylesterase that in teosinte silks prevents fertilization by maize pollen.

The paper assesses how colorful bird feathers appear to mammalian predators using visual modeling, finding they are often cryptic to these predators but visible to birds.

The paper develops a microchip-based sequential secretion assay to analyze protein dynamics in single human macrophages, revealing distinct activation modes and states dependent on basal conditions.

This paper develops a platform to multiplex profile single-cell EV secretion, revealing heterogeneity in EV phenotypes and secretion patterns in OSCC cells.

This study compares the venom effectiveness of fire ant queens and workers, finding queen venoms act faster to knock down competitors than worker venoms.

The paper presents cryo-EM structures of the human 26S proteasome in seven conformational states during polyubiquitylated protein degradation, revealing dynamic substrate-proteasome interactions and ATP hydrolysis mechanisms.

The paper analyzes the distribution and genetic diversity of ammonia-oxidizing archaea (AOA) lineages in global oceans using metagenomics data, revealing distinct ecological patterns and environmental correlations.

The paper identifies a voltage-gated potassium channel in African mormyrid electric fish that evolves under positive selection and modifies action potential duration through unique biophysical properties.

This study shows that liraglutide reduces obesity-induced kidney injury by restoring renal lipid and energy metabolism through metabolic and molecular mechanisms.

The paper examines whether artificial selection for domestication traits in maize and sorghum targets orthologous genes, finding that while some genes show parallel selection, most targeted genes are non-overlapping.

This study identifies three states of the ATP-gammaS-bound human proteasome, showing nucleotide-driven remodeling of the AAA-ATPase channel controls CP gate opening.

The paper determines the cryo-EM structure of the human proteasome regulatory particle bound to p28, revealing its dynamic conformational landscape and role in proteasome assembly.