TP53 mutations promote immunogenic activity in breast cancer
Z. Liu, Z. Jiang, Y. Gao…·X. Wang
This study finds that TP53 mutations in breast cancer increase immunogenic activity, suggesting they could be a biomarker for immunotherapy response.
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286 papers
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Z. Liu, Z. Jiang, Y. Gao…·X. Wang
This study finds that TP53 mutations in breast cancer increase immunogenic activity, suggesting they could be a biomarker for immunotherapy response.
C. Liu, Y. Jing, D. Kang…·B. Yu
This study shows MITA regulates BCR signaling through actin reorganization via the PI3K pathway, affecting B cell differentiation and autoimmune disease.
Z. Wang, J. Xie, L. Guo…·Z. Liu
The paper identifies and maps the stripe rust resistance gene YrTZ2 in wild emmer wheat and compares its genomic region with Aegilops tauschii.
X. Wang, C. Wang, C. Ji…·X. Liu
This study isolates and characterizes Bacillus amyloliquefaciens subsp. plantarum XH-9, showing it promotes plant growth and suppresses Fusarium oxysporum in wheat.
Z. Liu, C. Torresilla, Y. Xiao…·B. Barbeau
This study shows that HIV-1 antisense protein (ASP) from different clades induces autophagy through interaction with p62 and is regulated by autophagy and ubiquitin/proteasome systems.
T. Liang, R. Guan, G. Cao…·Z. Wang
This study compares the antioxidant activity of C3G and C3G liposomes in 2D and 3D cell cultures, finding greater effects in the 3D model.
P. K. Zuber, I. Artsimovitch, M. NandyMazumdar…·S. H. Knauer
The paper shows RfaH, a transcription factor, binds to a hairpin structure in the non-template DNA strand via a conserved pause sequence, revealing a new mechanism for transcriptional regulation.
D. Ayeni, B. Miller, A. Kuhlmann…·K. Politi
The paper shows that erlotinib and oncogene withdrawal in EGFR mutant lung tumors increase infiltration of inflammatory immune cells, suggesting immunostimulatory effects of tumor regression.
K.-H. Lu, J. Cao, S. Oleson…·Z. Liu
This study shows that vagus nerve stimulation increases gastric emptying in rats by relaxing the pyloric sphincter, measured using MRI.
The paper uses simulations to study how denaturants affect the folding pathways of the PDZ3 domain, revealing concentration-dependent flux changes through intermediates.
Z. Liu, M. Li, Z. Jiang, X. Wang
This study identifies immune-related gene-sets with higher expression in TNBC, associated with survival prognosis and immune features like Treg cells and immune checkpoints.
W. Li, X. Zhang, X. Lu…·J. Liu
The paper identifies 5hmC signatures in cfDNA as accurate biomarkers for detecting colorectal and gastric cancers, outperforming conventional markers and matching tissue biopsy results.
Z. E, T. Li, H. Zhang…·C. Chen
This study identifies and characterizes NF-Y transcription factors involved in rice endosperm development, showing sub-functionalization and interaction patterns among subunits.
H. Liu, P. Dong, M. S. Ioannou…·Z. Liu
This paper introduces a genetic strategy for sparse protein labeling in live cells, enabling long-term single-molecule tracking and revealing new insights into molecular dynamics in vivo.
L. Zheng, Y. Zhong, Y. Gao…·L. Ren
This study investigates how morphology and mechanical properties of snake scales influence tribological behaviors, proposing a 'double-crossed' hypothesis to explain their coupling effect.
This study identifies 208 imprinted genes in rice, showing limited transposable element association, intraspecific variation, and conservation of imprinting at some loci across plant species.