Author
Z. Liu
Karolinska InstitutetPrimary ORCID profile (0009-0003-3836-7377 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2017-2025 · peak 77/yrCo-Author Collaboration Network
10 top collaborators · 38 mutual co-author links294 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
A Novel Non-hypermucoviscous ST11 Hypervirulent Carbapenem-resistant Klebsiella pneumoniae Lacking Classical Virulence Factors
M. Zhang, J. Zhang, J. Li…·W. Huang
This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.
DOI 10.1101/2020.02.28.970863 - Evolutionary BiologybioRxivPreprint
Polyploidization enhancing genetic recombination of the ancestral diploid genome in the evolution of hexaploid wheat
This study shows that hexaploidization in wheat enhances genetic recombination of the ancestral diploid genome, increasing evolutionary potential and aiding wheat's global spread.
DOI 10.1101/2020.02.21.958991 - Plant BiologybioRxiv
Global Dynamic Molecular Profiles of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing
Z. Liu, Y. Zhou, J. Guo…·X. Sun
The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.
DOI 10.1016/j.molp.2020.06.010 - BiochemistrybioRxivPreprint
Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiate the DNA damage response and repair
F. Meng, M. Qian, B. Peng…·B. Liu
This study shows that SIRT1 and SIRT6 work together to recognize DNA breaks and enhance the DNA damage response and repair.
DOI 10.1101/2020.02.01.930172 - Cell BiologybioRxiv
LRRK2 and Rab10 Coordinate Macropinocytosis to Mediate Immunological Responses in Phagocytes
Z. Liu, E. Xu, H. Zhao…·A. B. West
This study shows LRRK2 and Rab10 coordinate macropinocytosis in phagocytes, with LRRK2 phosphorylating Rab10 to block cargo recycling and promote signaling endosome maturation.
- MicrobiologybioRxivPreprint
A single nonsynonymous mutation on gene encoding E protein of Zika virus leads to increased neurovirulence in vivo
DOI 10.1101/2020.01.20.912535 - Cancer BiologybioRxivPreprint
Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with glioblastoma
R. Yang, G. Huang, J. Guo…·Y. Liu
This study identifies stem cell-like GBM cells outside the contrast-enhancing region and proliferative lymphocytes in GBM patients' blood, linking them to recurrence and immunotherapy.
- Plant BiologyPLOS ONEPeer-reviewed
Transcriptional Differences of Peanut (Arachis hypogaea L.) Seeds in the Fresh-harvest, After-ripened and Just-germinated States: insights into regulatory networks of seed dormancy-release and germination
p. xu, G. Tang, W. Cui…·S. Wan
This study identifies transcriptional changes in peanut seeds during dormancy release and germination, revealing key pathways and hormone-related genes involved in these processes.
DOI 10.1371/journal.pone.0219413 - ZoologybioRxivPreprint
Aquaculture potential of Bohai Red and its hybrid with Agropecten irradians concentricus in southern China
This study introduces a new scallop strain, Bohai Red, and evaluates its hybridization with A. irradians concentricus, finding hybrids show improved survival, growth, and heat tolerance.
DOI 10.1101/2019.12.29.890160 - BiophysicsbioRxiv
Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure
K. Zhao, Y. Li, Z. Liu…·C. Liu
This study determines the cryo-EM structure of a novel α-synuclein fibril formed by the E46K mutation, showing structural changes and altered stability compared to wild-type fibrils.
- MicrobiologybioRxivPreprint
A Novel LysR-Type Global Regulator RpvA Controls Persister Formation and Virulence in Staphylococcus aureus
J. Han, Z. Liu, T. Xu…·Y. Zhang
This study identifies RpvA, a LysR-type regulator in S. aureus, which controls persister formation and virulence by modulating metabolism and virulence gene expression.
DOI 10.1101/861500 - Plant BiologybioRxiv
In vivo nuclear RNA structurome reveals RNA-structure regulation of mRNA processing in plants
Y. DING, Z. Liu, Q. Liu…·J. Cheema
The paper uses SHAPE profiling to study RNA structure in Arabidopsis nuclei and identifies structural features linked to mRNA splicing and polyadenylation.
DOI 10.1186/s13059-020-02236-4 - Evolutionary BiologybioRxivPreprint
Variation in the life history strategy of cells underlies tumor’s functional diversity
This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.
DOI 10.1101/829135 - ImmunologybioRxiv
Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a
C. Lai, l. liu, q. liu…·X. Wang
This study identifies lncRNA AVAN as a positive regulator of antiviral innate immunity by interacting with TRIM25 and enhancing FOXO3a transcription.
DOI 10.1038/s41418-021-00791-2 - Cell BiologybioRxivPreprint
Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production
The paper identifies MRISC cells as a novel intestinal stem cell niche that produces R-spondin1 via Map3k2 signaling to promote intestinal regeneration after damage.
DOI 10.1101/723221 - Cancer BiologybioRxiv
Coordinate Enhancer Reprogramming by GATA3 and AP1 Promotes Phenotypic Plasticity to Achieve Breast Cancer Endocrine Resistance
M. Bi, Z. Zhang, H. Wang…·Z. Liu
This study identifies GATA3 and AP1-driven enhancer reprogramming as a mechanism promoting phenotypic plasticity and endocrine resistance in breast cancer.
DOI 10.1038/s41556-020-0514-z - MicrobiologybioRxivPreprint
Lyb-2-4, a unique genomic region of hypervirulent carbapenem-resistant Acinetobacter baumannii
C. Zheng, J. Zhang, M. Zhang…·W. Huang
The paper identifies a genomic region Lyb-2-4 associated with hypervirulence in carbapenem-resistant Acinetobacter baumannii, showing higher mortality in infected patients and mice.
DOI 10.1101/768655 - Cancer BiologybioRxiv
Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors
A. J. Patel, Y.-W. Wan, R. Al-Ouran…·T. J. Klisch
This study identifies three molecular types of meningiomas that better predict recurrence than WHO grading and links aggressive tumors to loss of DREAM complex repression.
DOI 10.1073/pnas.1912858116 - Cell BiologybioRxivPreprint
Prognostic value of Red Blood Cell Distribution Width in Acute Kidney Injury Patients:A Systematic Review and Meta-analysis
Z. Liu, S. Wang, X. Yao, J. Xing
This meta-analysis evaluates the prognostic value of Red Blood Cell Distribution Width (RDW) in Acute Kidney Injury (AKI) patients, finding a significant association but noting limitations due to small sample sizes.
DOI 10.1101/750190 - Cancer BiologybioRxiv
Fibroblast growth factor receptor facilitates recurrence of minimal residual disease following trastuzumab emtansine therapy
S. S. Akhand, S. C. Purdy, Z. Liu…·M. Wendt
This study shows that FGFR1 promotes T-DM1 resistance and tumor recurrence in HER2+ breast cancer, suggesting FGFR inhibitors like FIIN4 could be combined with T-DM1 for better treatment.
DOI 10.1038/s41523-020-00213-5 - BiophysicsbioRxivPreprint
Apolipoprotein A-I Mimetic 4F Peptide Generates Amyloid Cytotoxins by Forming Hetero-oligomers with β-amyloid
B. Sahoo, M. Bekier, Z. Liu…·A. Ramamoorthy
The paper investigates how the 4F peptide interacts with β-amyloid to form toxic heteromers, reducing aggregation kinetics and increasing neurotoxicity.
DOI 10.1101/722983 - Plant BiologybioRxiv
Ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress
S. Hartman, Z. Liu, H. van Veen…·L. A. C. J. Voesenek
The paper shows that ethylene-mediated nitric oxide depletion pre-adapts plants to hypoxia stress by stabilizing ERFVII transcription factors.
DOI 10.1038/s41467-019-12045-4 - Evolutionary BiologybioRxiv
Local adaptation drives the diversification of effectors in the fungal wheat pathogen Parastagonospora nodorum in the United States
J. Richards, E. Stukenbrock, J. Carpenter…·T. L. Friesen
This study uses whole genome resequencing of 197 Parastagonospora nodorum isolates to show that local adaptation drives effector gene diversification and genomic selection in response to host resistance/susceptibility in U.S. wheat production regions.
DOI 10.1371/journal.pgen.1008223 - BiochemistrybioRxiv
Tyr1 phosphorylation promotes the phosphorylation of Ser2 on the C-terminal domain of RNA polymerase II by P-TEFb
Y. Zhang, J. E. Mayfield, S. Irani…·J. Brodbelt
The paper shows Tyr1 phosphorylation directs P-TEFb to phosphorylate Ser2 on RNA polymerase II CTD, altering its specificity and expanding CTD modification coding potential.
DOI 10.7554/elife.48725 - ImmunologybioRxiv
Fate mapping via Ms4a3 expression history traces monocyte-derived cells
Z. Liu, Y. Gu, S. Chakarov…·F. Ginhoux
The paper identifies Ms4a3 as a marker for tracking monocyte-derived cells and quantifies their contribution to tissue-resident macrophages during homeostasis and inflammation.
DOI 10.1016/j.cell.2019.08.009 - BioengineeringbioRxiv
Differential Effects of Afferent and Efferent Vagus Nerve Stimulation on Gastric Motility Assessed with Magnetic Resonance Imaging
K.-H. Lu, J. Cao, R. Phillips…·Z. Liu
This study compares the effects of afferent and efferent vagus nerve stimulation on gastric motility using MRI in anesthetized rats, finding afferent stimulation more effective.