L. Wang

This study identifies IRE-1's role in modulating autophagy and lipolysis during lipid perturbation-induced ER stress in C. elegans.

This study identifies YES1 amplification as a novel mechanism of resistance to EGFR inhibitors in lung cancer using transposon mutagenesis and clinical genomic analysis.

The paper introduces a solid-phase assay to measure dNTP pools, optimized for large-scale measurements and based on a modified polymerase method.

The paper identifies a new susceptibility gene in rice by analyzing TAL effector repertoires and their functional roles in bacterial leaf blight.

This study identifies novel germline V and J alleles in Rhesus macaques by analyzing BCR repertoires and validates them using whole genome sequencing and alignment reference.

This study identifies phospho-ERK as a biomarker for response to sorafenib and MEK inhibition in liver cancer, showing synergistic effects in tumors with high phospho-ERK levels.

This study identifies USP7 as a key driver of T-cell leukemia by stabilizing NOTCH1 and JMJD3, showing USP7 inhibition blocks leukemia growth and suggests it as a therapeutic target.

This study investigates how 1,25-dihydroxyvitamin D3 and fluid shear stress together affect osteoblast function, showing their combined impact on nitric oxide release, proliferation, PGE2 release, and differentiation.

This study identifies HNF1A as a central regulator of pancreatic cancer stem cells and a novel oncogene in pancreatic ductal adenocarcinoma.

The paper shows that HIG2 inhibits ATGL to promote lipid droplet accumulation in hypoxic cancer cells, supporting their survival by reducing ROS and apoptosis.

This paper introduces a new parameter, the packing coefficient, to analyze lateral subdiffusion in biological membranes and demonstrates its application in detecting changes in diffusive behavior.

This study identifies the role of N-linked glycosylation in ZIKV E protein function across mosquito and human cells using a mutant library.

The paper models how stochastic larval dispersal can enable upstream spread despite downstream currents, using green crabs in the Gulf of St Lawrence.

This study shows type 2 diabetes increases centrosome amplification in PBMCs through AKT-ROS-dependent activation of ROCK1 and 14-3-3σ.

The paper identifies BAM1 as a positive regulator of RNAi cell-to-cell spread and shows that a viral protein inhibits this process by interacting with BAM1 and BAM2.

This study introduces PACER, a network embedding method to identify pathways associated with chemosensitivity by integrating gene expression and molecular network data.

This study examines how demographic changes and selection shaped maize domestication and spread using genomic data from landraces and wild progenitors.

This study identifies and characterizes NF-Y transcription factors involved in rice endosperm development, showing sub-functionalization and interaction patterns among subunits.

This study identifies 208 imprinted genes in rice, showing limited transposable element association, intraspecific variation, and conservation of imprinting at some loci across plant species.

This study investigates how sodium ions regulate the oligomeric state and activity of cyanobacterial histidine kinase 2 through biochemical and structural methods.

This paper demonstrates a synthesis-free PET imaging method for brown adipose tissue and TSPO using Disulfiram and 64CuCl2, showing TSPO as a biomarker for BAT mass.

This study tests eDNA detection for invasive crayfish in rice terraces, finding it more sensitive than trapping and suggesting repeated sampling for reliable monitoring.