Y. Liang

This study compares the gut DNA and RNA viromes of Chinese residents and Pakistani visitors, finding ethnic origin significantly influences virome composition and diversity.

The paper uses digital spatial profiling to analyze coronary plaques from HIV-positive and HIV-negative individuals, finding higher CD163 and STING expression in HIV-positive plaques.

HiFi-SIM improves structured illumination microscopy image fidelity by reducing artifacts and enhancing axial resolution without requiring precise PSF calibration or parameter tuning.

This study presents MKK7 crystal structures and identifies new allosteric targets, revealing structural mechanisms of activation and potential drug candidates.

This paper describes a rapid method using LAMP and Nanopore Flongle for detecting SARS-CoV-2 and other respiratory viruses in under two hours.

This study shows that SIRT1 reduces premature senescence-induced defenestration in hepatic sinusoidal endothelial cells by deacetylating p53 and mitigating oxidative damage.

This study investigates lung inflammation and endothelial dysfunction in severe Orientia tsutsugamushi infection, identifying biomarkers of vascular disruption and M1-skewed inflammation.

This study identifies BRD9-containing non-canonical BAF complex as a regulator of Foxp3 in Tregs using a genome-wide CRISPR screen.

This study tracks the decline of mcr-1 prevalence and genetic changes in mcr-1-positive Escherichia coli after China banned colistin use in animal feed.

This study evaluates the efficacy of autodissemination of pyriproxyfen against Aedes sp. in Malaysia, showing significant population reduction in treated areas.

This paper introduces a drug discovery platform called SPEED that uses epitope editing to screen small molecules for altering antibody-epitope interactions and validates its application for Aβ species.

This study shows obesity increases TH2 immunopathology by disrupting PPARγ in T cells, and TZDs can protect against this effect in obese mice.

This paper develops an Agrobacterium-mediated transient transformation method for sorghum leaves to efficiently test vector constructs and genome editing tools.

This study identifies gut microbiome biomarkers associated with obesity in Shenzhen adolescents and finds gender-specific differences in microbiome composition and function.

This study identifies immune subtypes in AML and shows that IFN-gamma profiles predict chemotherapy resistance and immunotherapy response.

This study examines how century-long fertilization affects microbial community succession and assembly mechanisms in grassland soils.

The paper demonstrates a strong positive biodiversity-productivity relationship in a subtropical forest experiment, showing increased productivity with species richness and complementary effects over time.

This paper describes the fusion of DN and AflR genes to create a novel protein that enhances anti-A. flavus activity compared to DN alone.

The paper introduces a method to fine-tune fluorophores for improved brightness and photostability in live-cell and in vivo imaging.