Z. Wang

This study examines how children's basic knowledge levels relate to their concept activation abilities and reaction times in a science context, finding negative correlations and implications for divergent thinking.

This study evaluates the replicative ability and pathogenicity of SARS-CoV-2 BA.2.75 isolates in Syrian hamsters, finding higher lung replication and focal pneumonia compared to BA.2 and BA.5.

The paper shows that antigen presentation dynamics after multiple vaccinations influence the immune response to SARS-CoV-2 Omicron by shaping B cell responses and antibody targeting of epitopes.

This study develops molecular markers for KTI mutant alleles in soybean using CRISPR/Cas9 to aid in breeding low TI trait cultivars.

The paper shows that epistasis reduces the genetic barrier for SARS-CoV-2 variants to escape broadly neutralizing antibodies by enabling resistance through combinations of mutations.

This study identifies butyrate, a microbiota-derived metabolite, as a regulator of peripheral efferocytosis, showing its ability to restore impaired phagocytic clearance in antibiotic-treated mice.

MitoTNT tracks mitochondrial networks in 4D live-cell imaging data, revealing movement patterns and dynamic responses to pharmacological treatments.

The paper shows that FUS condensates during aging exhibit solid/liquid coexistence, with the transition initiated at the interface between dense and dilute phases.

This study compares memory B cell responses after Delta and Omicron BA.1 breakthrough infections versus mRNA vaccine doses, finding that Delta infection boosts overall memory B cell potency and breadth, while Omicron infection only enhances strain-specific responses.

The paper identifies two point mutations in PCDH1 that disrupt ANDV recognition and protect against lethal infection in Syrian hamsters.

This study shows that variations in cuticular hydrocarbons, particularly methyl-branched CHCs, largely explain desiccation resistance differences among Drosophila species.

This study edits two IDA homologues in Brassica napus to prevent petal shedding, enhance silique shattering resistance, and extend flowering period, without affecting agronomic traits.

The paper identifies Muribaculaceae family bacteria as pathobionts that induce insulin-dependent diabetes in mice through translocation to the pancreas following gut microbiota disruption.

This study identifies P-TEFb as a factor that promotes cell survival by suppressing the intrinsic apoptosis pathway when p53 is activated, suggesting its potential as a therapeutic target in combination with apoptosis inducers.

The paper uses a consumer-resource model to show that microbial strains can coexist in boom-and-bust environments by differentiating on Monod parameters, resulting in 1-3 strains coexisting despite theoretical limits.

This study shows that MI-503 inhibits gastrin gene expression by blocking Menin nuclear export in gastrinomas.

This study compares humoral immune responses to different SARS-CoV-2 vaccination regimens, finding differences in antibody and memory B cell responses and neutralizing breadth against variants.

This paper introduces Zeno SWATH, a high-throughput proteomics method that improves protein identification and quantification in small sample amounts using fast chromatography.

This study compares memory B cell responses after single-dose Ad26.COV2.S and mRNA vaccines, finding lower quantities but comparable neutralizing quality in Ad26.COV2.S recipients.

The paper introduces PanGu Drug Model, a deep learning architecture for drug discovery that achieves state-of-the-art results in molecule property prediction, generation, and optimization.

This study shows that SARS-CoV-2 accessory protein ORF8 reduces antibody-dependent cellular cytotoxicity by binding CD16a and decreasing CD16 surface levels on monocytes and NK cells.

This study shows CRISPR/Cas9 can induce exon skipping in β-catenin, creating gain-of-function mutations that drive distinct liver cancer subtypes in mice and are found in human HCC patients.

This study identifies climate-driven factors shaping nematode diversity in forest soils across different climatic zones.

This study shows that seasonality, not photoperiodism, affects the susceptibility of spider mites to pesticides, with toxicity increasing in spring and summer and decreasing in winter.

The paper improves a DNA polymerase's efficiency for unnatural nucleotide incorporation by identifying two key mutations through machine learning and mechanistic analysis.

This study identifies a new RORγt+ antigen-presenting cell type, Thetis cells, that drives microbiota-dependent regulatory T cell differentiation and tolerance during early life.

The paper identifies GATOR1 as a tumor suppressor in MYC-driven lymphomagenesis using in vivo CRISPR screens and shows its sensitivity to mTOR inhibitors.

This study shows that a third mRNA vaccine dose increases the potency and breadth of SARS-CoV-2 neutralizing antibodies, particularly against the Omicron variant, through the expansion and evolution of memory B cells.

The paper identifies miR-306 and miR-79 as tumor-suppressor miRNAs that eliminate JNK-activated tumors in Drosophila by non-canonical activation of JNK signaling through targeting dRNF146.

The paper identifies conserved neutralizing epitopes on the N-terminal domain of SARS-CoV-2 spike proteins using NTD-specific probes and characterizes antibodies that neutralize multiple variants.