Author

D. Zou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

H. Chen· 2 shared J. Huang· 2 shared L. Wang· 2 shared S. Chen· 2 shared A. Prabhu· 1 shared A. Q. He· 1 shared B. Xu· 1 shared C. Liao· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

H. Chen

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Macrophages as Key Mediators of Trp-1-Specific CD4+ T Cell Therapy for Murine Melanoma

A. Q. He, D. Zou, W. Chen

The paper investigates the role of macrophages in Trp-1-specific CD4+ T cell therapy for melanoma, finding that macrophages enhance antitumor effects.

bioRxiv · Dec 20, 2023 · PreprintImmunology

Gene inversion triggered origination of brackish archaeal heterotrophs in the aftermath of the Cryogenian Snowball Earth

L. Fan, B. Xu, S. Chen, Y. Liu, F. Li, W. Xie, A. Prabhu, D. Zou, R. Wan, H. Li, H. Liu, Y. Liu, S.-J. Kao, J. Chen, Y. Zhu, , C. Zhang

The paper traces the evolutionary origin of brackish archaea, showing gene rearrangements enabled their adaptation to coastal environments after the Cryogenian Snowball Earth.

bioRxiv · Sep 25, 2022Evolutionary Biology

Reduced virulence and enhanced host adaption during antibiotics therapy: A story of a within-host carbapenem-resistant Klebsiella pneumoniae sequence type 11 evolution in a fatal scrotal abscess patient

M. Ye, C. Liao, M. Shang, D. Zou, J. Yan, Z. Hu, X. Xu, J. Jiang, P. Zhou

This study tracks the genomic evolution of ST11-CRKP during antibiotic therapy in a patient, identifying mutations linked to reduced virulence and increased host adaptation.

bioRxiv · May 6, 2021Microbiology

Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution

L. Wang, J. Li, S. He, H. Chen, S. He, M. Yin, D. Zou, J. Xu, S. Chen, T. Luo, X. Yu, J. BEI, Z. Guo, X. He

The paper analyzes single-cell transcriptomes during liver transplantation to understand ischemia-reperfusion injury and identifies a protective role for TNIP3 in Kupffer cells.

bioRxiv · Jan 10, 2021Cell Biology

C1q/CTRP1 exerts neuroprotective effects in TBI rats by regulating inflammation and autophagy

M. Pei, C. Wang, Z. Li, J. Zhang, P. Huang, J. Wang, J. Huang, D. Zou, Y. Chen

This study investigates the neuroprotective role of CTRP1 in TBI rats, finding it reduces inflammation and modulates autophagy through mTOR activation.

bioRxiv · Dec 29, 2020 · PreprintPathology

Evaluation of the effect of life extension of DHEA extract from sweet potato on Caenorhabditis elegans

H. Chen, D. Zou, L. Wang, J. Huang

This study evaluates DHEA extract from sweet potato on C. elegans lifespan, finding it extends life by 13.60% but not via calorie restriction, and suggests antioxidant and daf-16 activation mechanisms.

bioRxiv · Dec 16, 2020 · PreprintBiochemistry

Hesperetin inhibits foam cell formation in macrophages via activating LXRα signal in an AMPK dependent manner

X. Chen, D. Zou, X. Chen, H. Wu, D. Xu

This study shows hesperetin reduces foam cell formation in macrophages by activating LXRα through AMPK-dependent mechanisms, enhancing cholesterol efflux and reducing cholesterol accumulation.

bioRxiv · Jan 22, 2020Pharmacology & Toxicology