R. Wu

The paper shows that the interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat by maintaining brown adipocyte identity and thermogenic function.

The study uses mass cytometry to analyze immune cell subsets in convalescent COVID-19 patients, linking monocyte and T cell populations to disease severity and clinical markers.

This study identifies NTF3 as a fat-derived neurotrophic factor that regulates sympathetic innervation and thermogenesis in adipose tissue, influencing energy metabolism and obesity.

This study shows that polyamine homeostasis in T cells is regulated by de novo synthesis and salvage pathways, affecting proliferation and function, with implications for inflammatory and autoimmune diseases.

The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.

This paper introduces a high-throughput drug screening method called CEBIT that detects biomolecular interactions and enzyme inhibitors by using phase-separated compartments.

This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.

This study shows that ApoA1 deficiency impairs Treg cell homeostasis and function through reduced IL-2 signaling and altered cholesterol content in mice.

This study identifies immune-related genes under positive selection in schizothoracine fish, linking their adaptive evolution to speciation and local adaptation on the Qinghai-Tibetan Plateau.

The paper investigates pre-existing adaptive immune responses to CRISPR Cas proteins and AAVs in non-human primates and finds such immunity is普遍存在 regardless of Cas proteins or AAVs.

This study identifies G-quadruplex-forming regions in human ribosomal RNA, specifically in Expansion Segment 7, and shows their presence in chordate LSU rRNA.

This study identifies circZKSCAN1 as a negative regulator of cancer stem cells in hepatocellular carcinoma, revealing its mechanism through interaction with FMRP and CCAR1-Wnt signaling.

This study identifies and genotypes Trichosporon species isolated from giant pandas, finding 11 species with varying pathogenicity and genotypes.

The paper shows CCL3 promotes B cell interactions with follicular regulatory T cells in germinal centers, enhancing their negative regulation.

This study characterizes BaaR, an IclR-family repressor in Brucella abortus, showing it represses carboxylic acid oxidation operons and is activated by specific organic molecules.