Author

S. Jackson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2 Plant Biology· 2 Bioengineering· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:Arabidopsis· 2 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

M. Dunn· 2 shared M. J. Klein· 2 shared P. N. Paradkar· 2 shared A. A. Hoffmann· 1 shared A. Blackford· 1 shared A. Burns· 1 shared A. Civitarese· 1 shared A. Eisenberg· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

M. Dunn

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Author profile →

11 papers

Recent·Most cited

The J-Like Protein ARC6 Regulates Chloroplast FtsZ-Ring Assembly through Fine-tuning ARC3 Activity in Arabidopsis

W. Du, L. Cao, Y. Zhou, S. Jackson, M. Naeem, Y. Yang, J. Glynn, K. Porter, Q. He, J. Xu, W. Liang, K. W. Osteryoung, C. Chen

The paper identifies ARC6 as a regulator of chloroplast division by modulating ARC3 activity through its J-like domain, ensuring proper Z-ring assembly and positioning.

bioRxiv · Jan 8, 2024 · PreprintPlant Biology

The potential of Senicapoc, a KCNN4 inhibitor, for the prevention and treatment of breast cancer

G. Chenevix-Trench, K. Britt, C. Xiao, M. Miranda, W. Shi, J. Beesley, J. Saunus, A. Civitarese, D. Black, M. Ruppert, M. Perreira, S. Jackson, Z. Teale, D. Carter-Cusack, L. Kalinowski, , F. Al-Ejeh

This study investigates Senicapoc, a KCNN4 inhibitor, and finds it delays mammary tumor development and slows tumor growth in mouse models, suggesting potential for breast cancer prevention and treatment.

bioRxiv · Apr 25, 2023 · PreprintCancer Biology

Engineered Antiviral Sensor Targets Infected Mosquitoes

E. Dalla Benetta, A. J. Lopez-Denman, H.-H. Li, R. A. Masri, D. J. Brogan, M. Bui, T. Yang, M. Li, M. Dunn, M. J. Klein, S. Jackson, K. Catalan, K. R. Blasdell, P. Tng, I. Antoshechkin, , O. Akbari

The paper develops REAPER, a Cas13-based antiviral sensor that kills infected mosquitoes upon activation by arbovirus infection.

bioRxiv · Jan 27, 2023Bioengineering

Developing Wolbachia-based disease interventions for an extreme environment

P. A. Ross, S. Elfekih, S. Collier, M. J. Klein, S. S. Lee, M. Dunn, S. Jackson, Y. Zhang, J. K. Axford, X. Gu, M. S. Nasar, P. N. Paradkar, E. A. Tawfik, F. M. Jiggins, A. M. Almalik, , A. A. Hoffmann

This study evaluates Wolbachia strains in Saudi Arabian mosquitoes for dengue suppression in extreme environments, finding reduced heat tolerance and local adaptation effects.

bioRxiv · Jul 26, 2022Evolutionary Biology

Ecosystem services in connected catchment to coast ecosystems: monitoring to detect emerging trends

C. J. Brown, C. Saint Ange, R. Connolly, S. Hasan, S. Jackson, J. McMahon, J. Smart

The paper tests ecological indicators in a catchment-to-coast system to determine their response times to environmental change, finding they require over 10 years to detect trends.

bioRxiv · Jul 19, 2021Ecology

Structural basis of drug recognition by the multidrug transporter ABCG2

J. Kowal, D. Ni, S. Jackson, I. Manolaridis, H. Stahlberg, K. P. Locher

This study presents cryo-EM structures of ABCG2 bound to anticancer drugs, revealing how it recognizes and binds exogenous compounds and the structural basis for drug-induced ATPase activity.

bioRxiv · Feb 18, 2021Biophysics

Reappraisal of Spinach-based RNA Visualization in Plants

Z. A. Yu, F. Mei, H. Yan, Q. Chen, M. Yao, S. Liu, Y. Wang, X. Zhang, P. Zhang, S. Jackson, N. Shi, Y. Liu, Y. Hong

This study reevaluates Spinach-based RNA visualization in plants, showing potential for ex vivo and in vivo RNA monitoring.

bioRxiv · Sep 24, 2020 · PreprintPlant Biology

Signalome-wide assessment of erythrocyte response to Plasmodium reveals novel targets for host-directed antimalarial intervention

J. Adderley, S. John non Freyend, S. Jackson, M. Bird, A. Burns, B. Anar, T. Metcalf, J.-P. Semblat, O. Billker, D. Wilson, C. Doerig

The paper assesses host erythrocyte signaling during Plasmodium infection and identifies c-MET and B-Raf as potential targets for antimalarial intervention.

Nature Communications · Aug 11, 2020Peer-reviewedMicrobiology

Rapid Prototyping of Wireframe Scaffolded DNA Origami using ATHENA

H. Jun, X. Wang, W. Bricker, S. Jackson, M. Bathe

ATHENA is an open-source software that automates wireframe DNA origami design using 2D/3D geometries and 2HB/6HB edges, enabling sequence generation and integration with simulation tools.

bioRxiv · Feb 9, 2020Biophysics

Mitochondrial replacement in an iPSC model of Leber Hereditary Optic Neuropathy.

R. Wong, S. Y. Lim, S. S. Hung, S. Jackson, S. Khan, N. J. Van Bergen, E. De Smit, H. H. Liang, L. S. Kearns, L. Clarke, D. A. Mackey, A. Hewitt, I. A. Trounce, A. Pebay

The paper uses cybrid technology to replace mtDNA mutations in iPSCs derived from LHON patients, showing reduced RGC death in corrected cells.

bioRxiv · Mar 26, 2017Cell Biology

Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

A. Henssen, R. Koche, J. Zhuang, E. Jiang, C. Reed, A. Eisenberg, E. Still, I. MacArthur, E. Rodriguez-Fos, S. Gonzalez, M. Puiggros, A. Blackford, C. Mason, E. De Stanchina, M. Gonen, , A. Kentsis

This study identifies PGBD5 as an oncogenic DNA transposase in rhabdoid tumors, causing site-specific genomic rearrangements through PSS sequences and end-joining repair.

bioRxiv · Feb 23, 2017Cancer Biology