High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combine with droplet microfluidics
Y. Li, J. Qi, Y. Liu, Y. Zheng, H. Zhu, Y. Zang, X. Guan, S. Xie, H. Zhao, Y. Fu, H. Xiang, W. Zhang, H. Chen, H. Liu, Y. Zhao, , Y. Liu
The paper develops a high-throughput platform for screening functional neo-antigens and their specific TCRs using droplet microfluidics and DNA barcoding.
bioRxiv · Feb 20, 2023 · PreprintBioengineering