J. Song

This study identifies decorin as a negative regulator of E-cadherin in inflammatory breast cancer, showing it reduces migration, invasion, and metastasis by destabilizing E-cadherin and inhibiting EGFR/ERK signaling.

The paper identifies ANKLE1 as a nuclease that specifically cleaves branched DNA structures, suggesting its role in resolving DNA junctions during mitosis.

This study shows ATP induces protein folding, inhibits aggregation, and stabilizes proteins by mediating water-protein-ion interactions, with triphosphate being key but aggregation-prone, while ATP prevents this.

The paper investigates the ability of Arhopalus rusticus to transmit pine wood nematodes, finding that 12 beetles can transmit the nematodes through feeding on pine needles.

The paper uses computational fluid dynamics to analyze how owl tail postures affect drag during gliding, finding that observed postures minimize total drag.

This study measures wing shape and pose changes in barn owls during gliding at different speeds, finding that wing shape remains consistent while tail and posture adjustments modulate aerodynamic forces.

This study develops a novel preclinical model to assess long-term effects of precision radiation on salivary function and tissue integrity in mice.

The paper establishes a zebrafish model of G6PD deficiency that replicates key clinical features observed in humans with the condition.

This paper establishes a stable transgenic zebrafish model of G6PD deficiency that mimics clinical features and shows reduced GSH levels and G6PD abundance.

This study shows that endothelial basement membrane laminins 411 and 511 influence monocyte differentiation to macrophages by modulating migration and integrin profiles.

The paper shows that infant-directed speech and song across cultures share consistent acoustic features that can be reliably classified and are perceptible to listeners.

The paper analyzes insertion mutants in the HIV-1 gp41 C-terminal heptad repeat, finding that alanine insertion (653+A) attenuates membrane fusion due to slower 6HB formation kinetics, not 6HB stability.

This study identifies DNA deformation as a mechanism regulating DRM2-mediated methylation specificity in plants, showing how substrate deformation influences substrate preference.

This paper investigates how DHHC20 reshapes membranes to facilitate catalysis through biochemical and computational methods.

This study investigates how the feeding behavior of Monochamus alternatus affects the departure of pine wood nematodes, finding no significant difference but linking increased motility and oxidative phosphorylation to nematode departure.

This study identifies lncRNA AVAN as a positive regulator of antiviral innate immunity by interacting with TRIM25 and enhancing FOXO3a transcription.

This study develops a hydrogel platform to assemble human stem cell-derived β cells and endothelial cells into functional three-dimensional islet organoids.

The paper uses scanning transmission X-ray microscopy to identify dense granules in human platelets and reduces false detection compared to traditional TEM methods.

This study uses mass cytometry to analyze how silver nanoparticles interact with different human immune cells at the single-cell level, revealing differences in association and toxicity across cell types.

This study identifies flowering-time genes in mast flowering plants using transcriptomic analysis of two alpine species to understand their molecular regulation.

The paper uses shotgun metagenomics to analyze the gut microbiome in AS patients, finding enriched bacterial epitopes linked to HLA-B27 and effects of TNFi therapy and host genotype on microbiome composition.

This study uses 3D computational fluid dynamics to explain muscle activation patterns and energy dynamics in fish swimming, revealing how torque, power, and body elasticity contribute to different swimming modes.

This study shows that YxaL, a secreted protein from Bacillus velezensis, promotes plant growth and stress tolerance in Arabidopsis, rice, and pepper.

This study investigates the fracture behavior of defective popgraphene using molecular dynamics and continuum modeling, revealing how different defect types affect fracture stress.

This study identifies the TMEM106B cytoplasmic domain as intrinsically disordered, enabling its dynamic and transient interactions with multiple proteins.

The paper identifies structural capacitance as a new mechanism in protein evolution that generates microstructure in disordered regions, linking it to disease and evolutionary adaptability.

The paper identifies genes and transposons affected by context-specific DNA methylation changes in maize mutants, revealing distinct regulatory patterns for CMT and RdDM pathways.