F. Li

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

This study shows that HMGB1 release in response to mechanical overloading causes inflammation and tendinopathy in mice, which can be blocked by glycyrrhizin.

This study shows that Crif1 promotes radiation-induced osteoporosis in mice by increasing RANKL expression and that targeting Crif1 could be a therapeutic strategy.

This study shows lung cancer exosomes promote MDSC expansion via miR-21a/PDCD4/IL-6/STAT3 pathway, enhancing tumor growth.

This study identifies BCAT1-mediated metabolic reprogramming as a mechanism of EGFR TKI resistance in lung cancer and shows that combining TKI with ROS-inducing agents can overcome resistance.

The paper investigates the origin of breast milk microbes and identifies Bifidobacterium breve transmission via the enteromammary pathway in a C-section infant.

The paper introduces a FRET-based tension sensor to measure forces generated by NMIIB in living cells, revealing spatial and temporal heterogeneity in cytoskeletal forces.

The paper creates a gene catalog of bovine rumen microbes, revealing high diversity and function in plant biomass degradation and methane production.

This study identifies SKI-73 as a CARM1 chemical probe that reduces breast cancer cell invasion by altering epigenetic plasticity, distinct from CARM1 knockout effects.

This study identifies a PRMT7 inhibitor and shows its effect on arginine methylation of stress proteins, linking PRMT7 to cellular stress response.

This paper elucidates the compartmentalized biosynthetic pathway of mycophenolic acid, revealing subcellular localization of enzymes and cooperation with β-oxidation machinery.

This study shows low-dose IFN-γ promotes tumor stemness in NSCLC via ICAM1-PI3K-Akt-Notch1 pathway, while high-dose IFN-γ induces apoptosis through JAK1-STAT1-caspase pathway.

The paper examines resistance to Puccinia coronata f. sp. avenae in Brachypodium species, finding race-specific responses independent of ROS and involving salicylic acid and ethylene signaling.

This study meta-analyzes seven studies to show that exclusive breastfeeding increases gut microbiota diversity and specific metabolic pathways while reducing others, with benefits persisting beyond six months.

The paper sequences the genome of a diabetes-prone desert rodent and identifies a mutation hotspot around the ParaHox gene cluster, including the Pdx1 gene, showing extreme divergence due to GC-biased mutation.