A force-sensitive adhesion GPCR is indispensable in normal equilibrioception
Z. Yang, S. Zhou, Q. Zhang, Z. Song, W. Liu, Y. Sun, M. Wang, X. Fu, K. Zhu, Y. Guan, J. Qi, X. Wang, Y. Sun, Y. Lu, Y. Ping, , J. Sun
This study identifies LPHN2/ADGRL2 as a force-sensitive adhesion GPCR essential for normal equilibrioception by regulating mechanoelectrical transduction in utricular hair cells.
bioRxiv · Oct 24, 2023 · PreprintPhysiology