J. Jiang

The paper reports cryoEM structures of the mitochondrial SAM complex from Myceliophthora thermophila, revealing its architecture and mechanism for substrate accommodation.

This study shows senescent stromal cells release sEVs that promote cancer drug resistance via SIRT1 loss, and suggests targeting SIRT1 could prevent this resistance.

This study identifies DNA deformation as a mechanism regulating DRM2-mediated methylation specificity in plants, showing how substrate deformation influences substrate preference.

This study identifies EP2 as a key PGE2 receptor promoting neuroblastoma growth and shows that targeting it with small-molecule antagonists inhibits tumor growth in mice.

The paper identifies miR-486-5p and miR-22-3p as drivers of megakaryocytic differentiation in HSPCs without thrombopoietin, and shows MkMPs induce this through JNK and PI3K/Akt/mTOR signaling.

The paper evaluates how micrograzers control chytrid infections in amphibians by modeling their grazing impact on zoospores.

The paper shows MEcPP coordinates auxin and ethylene signaling via phytochrome B to regulate hypocotyl growth in response to light.

This study shows sucrose promotes potato stem branching by increasing cytokinin levels and vacuolar invertase activity in lateral buds.

This study shows RTR-1, a compound from Rhodomyrtus tomentosa, inhibits gastric cancer cell proliferation by inducing ER stress and blocking the STAT3 pathway, while causing G2/M phase cell cycle arrest.

This study found that a significant proportion of E. coli isolates from ready-to-eat lettuce in Northern California carry beta-lactam resistance genes, posing a potential risk for human infections.

This study examines evolutionary changes in the phosphoenolpyruvate transporter (PPT) during C4 photosynthesis emergence, identifying shifts in expression, light responsiveness, and cis-element acquisition in PPT1.

This paper identifies that CT1's interaction with Cx43's carboxyl terminal H2 domain, not ZO-1, mediates its protective effects against ischemia-reperfusion injury in the heart.

The study detects Wolbachia in wild Ae. aegypti mosquitoes from New Mexico and Florida, but not in Texas, and identifies the wAlbB strain.

The paper uses single-cell transcriptomics to identify novel cell states in healthy and asthmatic lung tissues, revealing changes in cell communication and immune responses.

This paper introduces a simple method to co-purify genomic DNA, RNA, and proteins from the same samples, reducing precipitation steps and enabling high-throughput analyses.

The paper compares hair follicle and eccrine sweat gland density across macaques, chimpanzees, and humans, finding humans have lower hair density and higher sweat gland density than other primates.

This study shows hemolysin facilitates cytosolic LPS sensing by liberating bacterial outer membrane vesicles, leading to inflammasome activation and gut inflammation.

The paper identifies and validates single-copy gene markers for phylogenomic studies in ray-finned fishes using comparative genomics and empirical testing across 83 species.

This paper identifies HpaM, a novel FAD-dependent monooxygenase in Alcaligenes faecalis JQ135, which catalyzes 2-decarboxylative hydroxylation of 5HPA to produce 2,5-DPH.

This paper introduces a multi-locus DNA barcoding framework to improve species identification, showing it works better than single-locus methods in some cases.