J. Jiang

This paper introduces microfluidic cantilevers for single-cell mass measurement, achieving sub-nanogram sensitivity and demonstrating improved performance with polymer materials.

This paper introduces single-objective evanescent scattering microscopy for label-free single protein imaging and binding kinetics quantification with high spatiotemporal resolution.

This study identifies hedgehogs as the major amplifying hosts of SFTSV, showing they can sustain viral transmission cycles with ticks in both laboratory and natural settings.

This study investigates how photothrombotic stroke disrupts neurovascular coupling and shows that acute recovery of this coupling predicts sensorimotor function recovery.

This study maps chromatin reprogramming and transcriptional regulation during hexaploid wheat embryogenesis, revealing epigenetic mechanisms governing cell fate and organogenesis.

This study shows that SVP interacts with TPL to repress flowering by inhibiting FT gene expression in chrysanthemum and Arabidopsis, highlighting a conserved mechanism across species.

This study shows that enteroblasts in Drosophila midguts re-enter mitosis and dedifferentiate into intestinal stem cells via EGFR-Ras signaling, revealing a mechanism for tissue regeneration.

This study identifies 322 viruses in 34 grasshopper species, including 202 novel species, and finds phylogenetic congruence between grasshoppers and certain viral families.

The paper shows that osteocytic Cx43 hemichannels mediate bone anabolic responses to mechanical loading via PGE2 release, and identifies them as a potential therapeutic target for bone loss.

This study shows that CD147 antibody inhibits SARS-CoV-2 infection and cytokine storm in variants by blocking viral entry and reducing inflammatory responses.

The paper determines the structure of the Shaker Kv channel and reveals that slow C-type inactivation involves dilation of the selectivity filter.

This study shows that suppressing Chl a catabolism in ryegrass reduces heat tolerance by disrupting photosystem stability, ROS balance, and chloroplast structure under moderate heat stress.

This study shows that adding specific DAG motifs from potyviruses to non-aphid transmissible potexviruses can confer aphid transmission capabilities, with varying efficiency depending on the motif and host plant.

This paper develops a rat model for oxytocin-induced labor and evaluates its effects on maternal and neonatal outcomes, finding no evidence of oxidative stress in the newborn brain.

This study investigates how plasma-activated water (PAW) affects the viability and cellular responses of Fusarium graminearum, finding significant inhibition of microbial activity and damage to cell wall, membrane, and mitochondria.

This study shows TMEM120A does not mediate poking- or stretch-induced currents and identifies a specific coenzyme A-binding site through cryo-EM structures.

This study shows KDM4 promotes epigenomic changes in senescent cells, enhances the SASP, and presents a therapeutic target for age-related diseases.

This study tracks the genomic evolution of ST11-CRKP during antibiotic therapy in a patient, identifying mutations linked to reduced virulence and increased host adaptation.

This study shows that activation of ACC synthase 2/6 increases stomatal density and clustering in Arabidopsis leaves under drought by mediating Ca2+ levels in stomatal lineage cells.

This paper uses Maxent modeling to predict the global distribution of talaromycosis, identifying key environmental and epidemiological drivers.

The paper creates a database of 1,440 microsporidia species and analyzes their ecological and phenotypic diversity, finding broad host ranges and polar tube length as a determinant of tissue specificity.

This study shows Talaromyces marneffei induces M2 macrophage polarization by downregulating SOCS3 and activating TLR9, enhancing fungal survival.

This study develops self-assembling SARS-CoV-2 nanoparticle vaccines that induce protective immunity in mice through subcutaneous and oral administration.

The paper reports X-ray structures of synthetic nanobodies bound to SARS-CoV-2 RBD, revealing CDR loop interactions and epitope recognition details.

The paper identifies a mechanism by which H3K27me3 is recognized and transcriptionally repressed through the BAH-PHD-CPL2 complex in Arabidopsis.

This study uses fMRI to examine how the human hippocampus and medial temporal lobe represent spatial and reward information during memory-guided navigation.

The paper reports cryoEM structures of DNA-PKcs in inactive and activated forms, revealing structural changes in HEAT repeats that drive kinase activation.

The paper studies how IRE1 and PERK signaling branches coordinate during ER stress, finding mutual inhibition and differential sensitivity regulated by p58IPK.

The paper screens endophytic bacteria from Taxus chinensis for IAA and lipopeptide production, identifies non-toxic strains, and suggests their potential for biofertilizer use.

This paper presents a CAD system for pulmonary nodule detection that improves recall, reduces false positives, and optimizes time consumption using a multi-model ensemble approach.