X. Xu

The paper identifies a molecular crosstalk where PD-L1 and CD80 form a heterodimer, blocking inhibitory pathways but preserving CD28 activation, and shows how PD-L1 blockade affects CD80 expression.

This study develops a CRISPR-assistant trans enhancer to efficiently activate gene expression by combining dCas9-VP64/sgRNA with a CMV enhancer.

This paper identifies MraW as a DNA methylase in E. coli O157:H7, showing its role in motility, colonization, and virulence through genome-wide methylation and regulation of flagellar genes.

The paper identifies molecular mechanisms underlying constitutive photomorphogenic phenotypes in Arabidopsis by showing PIF instability in cop1 mutants and PIF overexpression suppresses these phenotypes.

This study evaluates fusidic acid and its hydrogenation derivative for antimicrobial and anti-inflammatory effects against Gram-positive bacteria and in a mouse model.

The paper develops a gene therapy system that uses telomerase activity to kill cancer cells in mice without affecting normal cells.

This study shows metformin improves uterine progesterone signaling in PCOS-like rats by reducing PGR and ER expression and correcting gene expression abnormalities.

This study shows SlARF10 regulates chlorophyll and sugar accumulation in tomato fruits by controlling starch synthesis and photosynthesis.

The paper uses STORM to reveal different actin structures in mouse sperm flagella, including a double-helix in the midpiece.

This paper introduces ctPCR, a CRISPR-based method for detecting and typing DNA, validated for HPV subtypes and cervical carcinoma cells.

This study shows MapZ forms a stable ring in Streptococcus mutans that guides FtsZ treadmilling, controlling cell division.

This study characterizes the pathogenicity of Pseudomonas syringae strains towards cherry and plum, identifying host resistance and optimizing laboratory assays.

This study uses 18F-FDG PET/CT imaging and molecular assays to assess BAT aging in LmnaG609G/G609G mice, finding reduced metabolic activity and increased apoptosis/senescence compared to wild-type mice.

The paper investigates how vegetative compatibility groups (VCGs) influence virulence of Verticillium dahliae on strawberry, finding that VCGs are strongly related to virulence levels and that VdAve1-containing isolates show higher early virulence.

This paper reviews the origin, functioning, and degradation of the Kobresia pygmaea ecosystem in the Tibetan highlands, identifying key factors affecting its resilience and carbon dynamics.

The paper evaluates inhibitors of mutant IDH1 and IDH2 using biochemical and cell-based assays to identify effective compounds for cancer therapy.