Stabilization of RRBP1 mRNA via an m6A-dependent manner in prostate cancer constitutes a therapeutic vulnerability amenable to small-peptide inhibition of METTL3
Y. Feng, Z. Li, J. Zhu, C. Zou, Y. Tian, J. Xiong, Q. He, W. Li, H. Xu, B. Xu, J. Shi, D. Zhang
This study identifies METTL3-mediated stabilization of RRBP1 mRNA via m6A in prostate cancer and develops small-peptide inhibitors to target this pathway.
bioRxiv · Sep 4, 2023Cancer Biology