D. Yang

This study identifies intrinsic cardiac adrenergic cells as contributors to septic cardiomyopathy by releasing norepinephrine that exacerbates cardiac dysfunction through β1-adrenergic receptor activation.

This study investigates the roles of RIG-I and MDA5 in SARS-CoV-2 infection, finding that MDA5 is critical for type I/III IFN response while RIG-I has an IFN-independent antiviral effect.

The paper develops a Unit Pipe Pneumatic model to simulate gas diffusion kinetics in xylem embolism measurements and finds it overestimates embolism resistance by 2-17%.

This study identifies somatic collagen mutations in gastric cancer linked to distinct tumor environments and survival outcomes.

This study combines an HMGN1 peptide with PD-L1 blockade to expand stem-like CD8+ T cells and enhance antitumor effects in mouse models.

This study produces dihydroquercetin in E. coli from glycerol by optimizing a biosynthetic pathway and engineering a plant cytochrome P450, achieving 239.4 mg/L of DHQ.

This study identifies immune markers, including HLA-DR and CTLA-4 expression on CD4 T cells, that predict HBsAg loss in chronic hepatitis B patients.

This study shows that SARS-CoV-2-specific T cell memory persists for at least 9 months in most convalescent COVID-19 individuals, with some responses lasting longer.

This study investigates the dynamic conformational equilibrium of the dengue virus NS3pro-NS2B complex and shows that proteolytic activity correlates with the population of the closed conformation.

This paper characterizes and models interference in electro-quasistatic HBC for miniaturized wearables, proposing a biophysical interference pickup model and presenting measurement results up to 250kHz.

This paper develops a biophysical model to analyze path loss variability in capacitive HBC channels by investigating inter-device coupling and fringe field effects using FEM simulations and measurements.

This study shows sclerostin directly increases FGF23 production in osteocytes, contributing to phosphate homeostasis regulation.

The paper identifies self-similar scaling relationships between calcium and membrane potential kinetics in SAN cells across species, enabling prediction of heart rate and body mass.

This study identifies KIM1 as a potential receptor for SARS-CoV-2 in the kidney, showing it binds RBD with similar affinity to ACE2 and facilitates viral entry.

This study shows that MSR1 restricts Chikungunya virus infection by activating autophagy through interactions with ATG12 and the ATG5-ATG12-ATG16L1 complex.

This study shows DDX5 resolves a G-quadruplex in STAT1 mRNA 5UTR, enabling STAT1 translation and interferon signaling in HBV-infected hepatocytes.

This paper introduces DNA nanoswitch barcodes for multiplexed detection of up to 6 biomarkers in a single assay, demonstrating mixed multiplexing of DNA, RNA, antibody, and protein.

The paper shows that Ca2+ and membrane potential transitions during action potentials in SAN cells are self-similar across species and autonomic stimulation, indicating long-range correlations in their kinetic behavior.

This study examines CD8+ T cell cytotoxicity in mild COVID-19 patients, finding reduced cytotoxic potential in elderly individuals over 80 years old.

The paper identifies a core transcriptional aging signature in murine hematopoietic stem cells, showing increased membrane-associated gene expression and age-related heterogeneity.

This study demonstrates that attenuated Salmonella typhimurium can deliver SARS-CoV-2 spike protein DNA to rats, inducing humoral immunity against SARS-CoV-2.

The paper examines the effects of SWCNT dopamine nanosensors on mouse microglia and introduces a passivation strategy to enhance biocompatibility and imaging performance.

This study shows that MSR1 promotes VSV infection in the spinal cord by acting as a receptor, and its absence reduces viral load and mortality in mice.

The paper shows that limited inhibition of multiple core pathways in a driver network effectively blocks metastasis in mouse breast cancer models.

This study shows that EED-induced Tregs suppress intestinal CD4+ T cell responses to oral vaccines, but not lymph node responses, and worsen stunting when depleted.

This study develops a computational strategy for in silico nanobody affinity maturation, achieving a 17.5-fold improvement in binding affinity for an anti-HIF-1α nanobody.

This study shows that STING deficiency increases CXCL10 expression, leading to higher viral loads and inflammation in alphavirus-induced arthritis in mice.

This study identifies new regulatory patterns of KZFP family zinc fingers that drive their rapid evolution by binding non-transposable element regions and positively regulating gene expression.

This study shows that Aire's CARD-mediated multimerization forms nuclear foci and affects transcriptional activity, but also increases susceptibility to PML body interactions, which can impair its function.

The paper investigates the binding of paroxetine and its analogs to the serotonin transporter using structural and biochemical methods, revealing how they stabilize the outward-open conformation and inhibit serotonin transport.