H. Sun

This study creates a single-cell transcriptome atlas of a non-human primate to explore SARS-CoV-2 targets and immune responses, identifying potential therapeutic targets and mechanisms linking IL6 to viral entry.

This study analyzes plastome sequences from Gentianeae to show gene tree discordance and evolutionary rate heterogeneity among plastid genes, suggesting the need for more nuanced phylogenomic approaches.

The paper shows that ITE, an AHR ligand, inhibits glioma cell migration and invasion by reducing MYH9 expression, which is critical for cell motility.

This study shows that copy number profiles are conserved in patient-derived xenografts (PDXs) through engraftment and passaging, indicating minimal impact from the mouse host on tumor evolution.

This study identifies the instability of the selectivity filter (SF) gate in TWIK-1 K2P channels as the primary cause of their low intrinsic activity.

The paper identifies MRISC cells as a novel intestinal stem cell niche that produces R-spondin1 via Map3k2 signaling to promote intestinal regeneration after damage.

This study optimizes fertigation for greenhouse strawberries by identifying the optimal levels of N, P, K, and water to maximize yield and SSC/TA ratio.

This study shows that effector T cells use inosine as an alternative carbon source under glucose restriction, enhancing anti-tumor function and bypassing tumor-imposed metabolic limitations.

This study shows that engineering CAR-T cells with CD103 improves their anti-tumor efficacy against E-cadherin positive tumors by enhancing infiltration, expansion, and persistence in vivo.

The paper quantifies residual protein expression in CRISPR-Cas9 knockouts using RNA-seq and SPS-MS3, identifying mechanisms of partial protein preservation and functional retention.

This paper introduces an AI model to design and fold alpha-helical proteins from amino acid sequences, achieving high accuracy and efficiency.

This study shows that low concentrations of melatonin promote cotton seed germination by enhancing antioxidant enzyme activity, reducing MDA, and modulating plant hormones like ABA and GA3.

This paper identifies a novel LEAFY allele in Arabidopsis thaliana No-0 that causes a flower-in-flower phenotype due to disrupted DNA-binding function.

The paper uses single-cell RNA sequencing to analyze antler stem cells, finding they form a homogeneous population with unique gene expression patterns and potential as a model for regeneration.

This study identifies transcription start sites and RNA cleavage sites in Mycobacterium smegmatis under aerobic growth and hypoxia, revealing regulatory mechanisms shared with Mycobacterium tuberculosis.

This study identifies Cyclin B3's specific role in facilitating metaphase-to-anaphase transition in mouse oocyte meiosis I, while showing it is not required for oocyte maturation or sister chromosome segregation.

This study identifies TUG1 as an oncogenic lncRNA in pancreatic carcinoma that promotes progression by sponging miR-382 to upregulate EZH2.