S. Mu

Integrating EM and Patch-seq data: Synaptic connectivity and target specificity of predicted Sst transcriptomic types

The paper predicts MET-type identities from EM data and shows they have distinct connectivity patterns and synapse targets.

ABL1 Kinase plays an important role in spontaneous and chemotherapy-induced genomic instability in multiple myeloma

This study shows that inhibiting ABL1 kinase reduces genomic instability and enhances the efficacy of chemotherapy in multiple myeloma.

Apurinic/apyrimidinic nuclease 1 drives genomic evolution contributing to chemoresistance and tumorigenesis in solid tumor

This study identifies APE1 as a driver of genomic instability in solid tumors, showing its role in chemoresistance and tumorigenesis through effects on DNA repair and genome stability.

Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies

This study identifies the structural and molecular mechanisms of two neutralizing antibodies against FMDV, showing they disrupt virus-receptor interactions and provide prophylactic and therapeutic benefits.

A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD

This study identifies a linear epitope on SARS-CoV-2 S-RBD recognized by a potent neutralizing antibody and shows its potential for vaccine design.

A rapid and efficient screening system for neutralizing antibodies and its application for the discovery of potent neutralizing antibodies to SARS-CoV-2 S-RBD

This paper introduces a rapid screening system to identify potent neutralizing antibodies against SARS-CoV-2 and demonstrates its effectiveness in discovering high-potency antibodies.