J. Kim

This study shows that IL-3 deficiency increases disease severity in mice infected with M. tuberculosis and HSV-1/HSV-2.

The paper shows SEC24D is critical for collagen secretion, while other SEC24 paralogs also contribute, explaining tissue-specific phenotypes in SEC24 mutations.

The paper investigates the role of Spc1 in yeast, showing it shields transmembrane segments from signal peptidase cleavage, thereby influencing substrate selection.

This study identifies replication stress in premalignant OPCs before glioma formation using stochastic profiling in a mouse model.

The paper identifies two small proteins, MHA1 and MHA1L, that modulate ACD6 activity in Arabidopsis thaliana, affecting growth and defense trade-offs through calcium influx regulation.

The paper designs a wearable electronic-skin for mental health monitoring, finding that upper arm and forearm are optimal wear locations by balancing human factors and biosignal accuracy.

This study identifies two binding sites between FOXO4 and p53 using NMR and calorimetry, revealing their roles in promoting p21 transcription and cell senescence.

This paper introduces an L1H-CS based SRUS imaging technique that improves image quality and reduces acquisition time for visualizing microvasculature in vivo.

This paper uses theoretical modeling to predict how lipid membranes influence mechanotransduction at focal adhesions by modulating traction forces and signaling.

This study shows that 3D spheroid culture of hMSCs under osteogenesis conditions leads to osteocyte-like differentiation, mediated by actin balancing in a condensed cell state.

This study uses a Gal8-GFP reporter system to compare endosomal escape efficiency of lipid nanoparticles with cholesterol versus phytosterols, finding that LNP-Sito shows significantly enhanced escape.

The paper shows that centromere drive is suppressed by two parallel pathways, with heterochromatin and kinetochore pathways differing in their suppression of selfish DNA effects.

The paper shows that Eip74EF rescues VCP mutant phenotypes in Drosophila, while miR-34 overexpression is lethal, suggesting different roles for miR-34 targets in ALS-FTD.

This paper presents a label-free method for classifying bone marrow white blood cells using 3D refractive index tomograms and deep learning, achieving high accuracy in subtype classification.

This study identifies 109 host factors interacting with SARS-CoV-2 RNA and reveals their roles in antiviral or proviral functions through RNP capture and knockdown experiments.

This paper introduces spatially expandable fiber-based probes for deep brain interface, enabling three-dimensional recording and stimulation of neural activity with high resolution and minimal tissue damage.

This study shows that deleting the insulin receptor in beta-cells improves glucose tolerance in some mice but not others, depending on age and diet.

This paper develops a LAMP assay for rapid identification of the invasive pest Mythimna loreyi using a species-specific sequence from the NADH dehydrogenase subunit 5 gene.

The paper identifies proximal tubule cell state and metabolism as coupled by nuclear receptors in kidney disease using single-cell RNA-sequencing.

The paper introduces iSLET, a method to track tissue-specific secretory proteins in live mice, demonstrating its use in labeling and identifying liver-specific secreted proteomes in blood plasma.

This study shows that Smad3 in smooth muscle cells prevents harmful plaque changes in atherosclerosis by blocking specific cell transitions that lead to calcification and inflammation.

This study shows that SPA1 kinase directly phosphorylates HY5, affecting its stability and activity to regulate photomorphogenesis in Arabidopsis.

This study shows that CRL3KLHL12 and CRL3KLHL41 regulate the unfolded protein response by influencing COPII coat assembly and UPR sensors in different cell lines.

This paper investigates the subcellular localization and spatial dynamics of xyl mRNAs in Pseudomonas putida mt-2, revealing they cluster away from the nucleoid and ribosomes, suggesting decoupled transcription and translation.

The paper shows that the plant NLR CCA309 targets P-type ATPase to cause membrane depolarization, calcium influx, and cell death during hypersensitive response.

The paper identifies transcriptional and chromatin-based mechanisms that generate and maintain constant protein amounts per cell despite changes in cell size.

This study identifies new genotypes of Orientia tsutsugamushi from South Korean scrub typhus patients using MLST, finding 10 new alleles and six novel sequence types, with ST48 being the most prevalent.

This paper demonstrates the use of mRNA nanotherapeutics to generate soluble hACE2 for rapid neutralization of SARS-CoV-2 in both circulation and mucosal sites.

The paper identifies bacterial proteins that bind to gas clathrates and alter their morphology, suggesting potential industrial applications for clathrate control.