Proliferative Exhausted CD8 T Cells Exacerbate Long-lasting Anti-tumor Effects in Human Papillomavirus Positive Head and Neck Squamous Cell Carcinoma
D. Cheng, K. Qiu, Y. Rao, M. Mao, L. Li, Y. Wang, Y. Song, J. Chen, X. Yi, X. Shao, S. H. Huang, Y. Zhang, X. Chen, S. Wu, S. Yu, , J. Ren
The paper identifies a proliferative exhausted CD8+ T cell cluster in HPV-positive HNSCC that correlates with better patient survival and suggests potential therapeutic implications.
bioRxiv · Oct 27, 2022Immunology