X. Liang

This study shows that antibiotic-induced gut microbiome disruption reduces vaccine response in mice and non-human primates, but recovery of microbiome diversity restores immune responses.

This study identifies a hypervirulent CRKP strain in Egypt carrying two plasmids with carbapenemase and virulence genes, highlighting the genetic basis of resistance and virulence.

This study identifies and characterizes AnHSD, a novel homoserine dehydrogenase from Arthrobacter nicotinovorans that exhibits high oxidation activity for L-homoserine, suggesting its role in bacterial catabolism.

This study identifies a unique GCN5 histone acetyltransferase complex in Plasmodium falciparum that regulates erythrocyte invasion and virulence by modulating chromatin states and gene expression.

The paper identifies a novel, targetable macrophage population in idiopathic pulmonary fibrosis using single-cell RNA-seq, CyTOF, and flow cytometry.

This study examines how energy substances, reactive oxygen species, enzyme activities, and endogenous hormones influence somatic embryogenesis and abnormal callus formation in Ormosia henryi Prain.

This study investigates the role of WRKY31 and signaling compounds in enhancing insect resistance in Pinus massoniana L. against Dendrolimus punctatus by modulating hormone signaling pathways.

The paper identifies VAB-10B and WDR-62 as distinct regulators of non-centrosomal microtubules using proximity labeling in C. elegans.

This paper introduces an ultra-compact dual-band smart NEMS magnetoelectric antenna for wireless energy harvesting and magnetic field sensing in implantable medical devices.

This paper develops a platform to display multiple protein therapeutics on extracellular vesicles, showing improved efficacy in inflammatory disease models compared to existing biologics.

The paper reports cryo-EM structures of GPBAR-Gs complexes, revealing structural features of bile acid recognition, allosteric effects, and biased signaling.

This study determines the structure of human ESCRT-I and shows it forms a helical assembly that scaffolds and mechanically drives membrane scission during HIV-1 budding.

This study investigates the functional differences of kinesin-II in Chlamydomonas, showing that changes in IFT velocity have a limited effect on ciliary length.

The paper develops a discrete model for co-culture cell migration and derives a reduced model under steady-state assumptions, comparing it to a full model to determine when simplification is valid.

The paper identifies a non-centrosomal microtubule organizing center in dendritic growth cones that establishes microtubule orientation, with perturbation causing reversed polarity.

This study compares the gut microbiota of captive and wild roe deer using 16S-rRNA sequencing, finding higher diversity in wild deer and differences in dominant bacterial phyla.

The paper shows that different quorum sensing signals (AHLs) induce prophages in soil bacteria, altering community structure by targeting specific taxa.

The paper identifies differentially expressed proteins in tumor-associated vascular endothelial cells of colorectal cancer and links some to angiogenesis and metastasis.

The paper uses high-throughput pyrosequencing to analyze salivary microbiota in individuals with and without H. pylori infection, finding that infection and eradication both alter oral microbiota structure, but H. pylori presence in saliva is not linked to gastric infection status.

This study reveals the flexible and elastic nature of the T6SS double tubular structure, showing it can deform into various shapes while maintaining function, and proposes a new contraction model.

The paper identifies CMV-specific TCRβ signatures as biomarkers for antiviral T-cell responses by analyzing TCRβ sequences from CMV-infected individuals.

This paper investigates how microbial Fe(III)-oxide reduction affects the transport of diffusible tracers and non-diffusible nanoparticles in soils over time.

This study tracks Dehalococcoides mccartyi population shifts in lab cultures and field sites by analyzing rdhA gene abundances, showing that electron acceptor availability drives population selection.

The paper uses crowdsourced analysis of gene expression data to identify molecular signatures predictive of susceptibility to respiratory viruses before and after exposure.

This study identifies E2F7 as a regulator of chemoresistance in BRCA2-deficient cells, showing its role in enhancing PARP inhibitor and cisplatin resistance through RAD51 upregulation.

This study identifies a mechanosensitive RhoA pathway mediated by G12 and Myosin VI that protects epithelia from acute tensile stress by increasing junctional actomyosin.

The paper investigates the interaction between the TIP60 chromo barrel domain and histone peptides, finding no binding observed through fluorescence polarization or isothermal titration calorimetry and presenting a crystal structure of the domain.