X. Liu

This paper directly observes electrically conductive pili (e-pili) in Geobacter sulfurreducens using atomic force microscopy, confirming their role in long-range extracellular electron transport.

This study uses a split NanoLuc luciferase assay to analyze the kinetics of mitochondrial protein import through the TIM23MOTOR complex, identifying rate-limiting steps and their dependence on precursor properties.

This study identifies CaMYB101 as an anthocyanin biosynthesis repressor in pepper through genome-wide R2R3-MYB analysis and virus-induced gene silencing.

This study uses a real-time femtosecond laser and microfluidic device to guide axon outgrowth by creating netrin-1 gradients, achieving 92% guided axon growth.

The paper develops Bayesian models to handle bridge ordinal ratings in disease staging and shows they reduce bias and precision loss in models.

The paper analyzes transcriptome dynamics during gametogenesis in Ulva mutabilis and identifies a conserved RWP-RK transcription factor involved in sexual reproduction.

This study compares two mRNA SARS-CoV-2 vaccines in nonhuman primates, showing that CV2CoV, with optimized non-coding regions, provides better immune responses and protection than CVnCoV.

The paper quantitatively links morphology and bite force capacity in leaf-cutter ants, showing that larger workers have disproportionately higher bite force due to increased muscle volume.

This study integrates multi-omics data to identify DUB functions and therapeutic targets, revealing key enzymes like USP14, UCHL5, and USP7 with potential in cancer therapy.

This study regenerates functional B lymphopoiesis from pluripotent stem cells (PSCs) using Runx1, Hoxa9, and Lhx2, producing antigen-specific antibodies and immune memory in B-cell deficient animals.

This study uses TMT-based proteomics to analyze the antibacterial effects of YACTH against Staphylococcus aureus, identifying 490 differentially expressed proteins and their biological pathways.

This study reports a pan-drug-resistant Klebsiella pneumoniae isolate carrying NDM-5 and MCR-8.2 genes, along with chromosomal resistance mechanisms to colistin and tigecycline.

This study uses single-nucleus RNA-seq and spatial transcriptomics to identify lineage-specific regulatory changes and candidate therapeutic targets in hypertrophy cardiomyopathy.

This study identifies transcription factors, protein kinase, and aspartic peptidase that synergistically regulate salicylic acid-induced reduction in ethylene biosynthesis in kiwifruit.

This study shows autophagosomes fuse with phagosomes to aid in the degradation of apoptotic cells in C. elegans, revealing a novel role for autophagosomes in phagosome maturation.

This study investigates how plasma-activated water (PAW) affects the viability and cellular responses of Fusarium graminearum, finding significant inhibition of microbial activity and damage to cell wall, membrane, and mitochondria.

This paper presents a drug candidate, NANA-Me, that prevents and treats ADAA-based diseases caused by pathogenic anti-spike antibodies in COVID-19 and vaccines.

This study shows that anti-aggregation strategies in microbial space colonization enhance competitive success by increasing Space Accessibility, offsetting lower growth rates or initial abundance.

This study identifies ERAD as a proteostasis checkpoint during β-selection, showing Sel1l deficiency causes ER stress and apoptosis, impairing β T cell development.

This study uses transcranial photoacoustic imaging to detect early-stage photothrombotic stroke in neonatal piglets, finding that HbO2 saturation can distinguish affected from control brain regions.

The paper investigates the genetic architecture of flowering in Silene hybrids, finding polygenic control with conditionally neutral allele effects depending on habitat.

This study compares clonal evolution across right-sided colon cancer, left-sided colon cancer, and rectal cancer patients, finding differences in evolutionary patterns and identifying polyclonal origins of lymph node and extranodal tumor deposits.

This study uses molecular dynamics simulations to investigate how the L210F mutation in dOrai affects channel structure and activation, revealing conformational changes that may enable constitutive opening.

This study identifies p17 as a viral protein that inhibits the cGAS-STING pathway by interacting with STING and disrupting TBK1 and IKKε recruitment.

This study identifies CcrZ as a regulator that couples DNA replication with cell division in pneumococci by controlling DnaA activity, ensuring proper chromosome inheritance.

This study shows that non-neutralizing antibodies targeting HIV-1 envelope regions reduce mucosal infection and virus burden in humanized mice through Fc-mediated effector functions.

This study shows TIR signaling enhances the interaction between EDS1/PAD4 and ADR1-L1 and promotes ADR1-L1 oligomerization, crucial for immune activation and cell death.

This study shows that Tmem138 is essential for rhodopsin transport across the photoreceptor connecting cilium and outer segment biogenesis, with its absence causing photoreceptor degeneration.

This study shows that increased neuropeptide Y1 receptor signaling contributes to β-cell dysfunction in type 2 diabetes and that inhibiting this receptor with BIBO3304 improves β-cell function and glycaemic control.