F. Zhang

This paper develops a transparent active ECoG array using ZnO-TFTs for electrophysiological monitoring, enabling simultaneous optical and MRI-compatible brain signal recording.

The paper analyzes aging and cancer by profiling ubiquitinome and RNA-seq data in mice, identifying H2A ubiquitination as a marker linked to prognosis and tumor microenvironment.

This study uses iterative transcription factor screening to generate microglia-like cells from human iPSCs, identifying a combination of TFs that efficiently differentiate iPSCs into microglia-like cells within 4 days.

This study identifies ORF7a proteins from sarbecoviruses as inhibitors of MHC-I antigen presentation, with a single amino acid difference affecting their function.

This study identifies a common mechanism for temperature sensing in TRPM8 and TRPV1 thermoTRP channels through water-protein interaction changes.

This study shows that Pkd2, a putative ion channel in fission yeast, allows calcium influx when activated by membrane stretching during cytokinesis.

The paper identifies two competing bacterial guilds in the gut microbiome that correlate with host health conditions and can classify multiple diseases across diverse populations.

This study identifies the N-terminal domain (NTD) of p53 as the major binding site for Cyclophilin D, revealing dynamic electrostatic interactions and a minimal binding region for mPTP regulation.

This study shows that chromatin features and DNA methylation significantly affect CRISPR-Cas9 mutagenesis efficiency and mutation profiles in Arabidopsis thaliana.

This study investigates enrofloxacin's ability to cross the blood-brain barrier in crucian carp and its impact on brain injury markers.

The paper assesses Trichodesmium diversity in the Red Sea using metagenomes and hetR gene phylotyping, finding that morphology and marker genes may not reliably reflect genetic diversity.

This study shows rhamnan sulfate reduces atherosclerosis and vascular inflammation in ApoE-/- mice by enhancing endothelial barrier function and inhibiting NF-κB pathway activation.

This study identifies DcATX1 as a histone methyltransferase that accelerates ethylene-induced petal senescence in carnation by regulating H3K4me3 levels and gene expression.

This study examines the effects of losing RNA-directed DNA methylation in Setaria viridis by analyzing methylation patterns and gene expression in drm1ab mutants, finding limited morphological and transcriptional consequences.

This study analyzes 27 human pathogenic RNA viruses to show they form multiple co-circulating lineages with low turnover rates, occupying non-competing epidemiological niches.

The paper systematically analyzes UG and Abi RTs, classifies them into three major classes, and demonstrates their association with defense functions and antiphage roles.

This study investigates FMD virus dynamics and immune responses in African buffalo, showing systemic infection, high viral loads, and strong immune responses despite mild clinical symptoms.

This study shows that disrupting Golgi structure by knocking out GRASP55 and GRASP65 alters glycosaminoglycan synthesis, sulfation, and secretion.

This study investigates how grafting affects anthocyanin synthesis in grapevines by analyzing metabolomic and transcriptomic profiles across different grafting conditions.

The paper develops SSR markers from drought stress-responsive miRNAs in Dongxiang wild rice and verifies their genetic diversity across DXWR and modern rice varieties.

This study identifies LbGH28A, a polygalacturonase from Laccaria bicolor, as essential for ectomycorrhiza formation by degrading pectin in fungal and plant cell walls during symbiosis.

This study identifies regional predictors of human-infective RNA virus discovery in the US, China, and Africa using ecological data and modeling, finding land use and socio-economic factors are most influential.

This study analyzes epistatic interactions among RBD mutations in SARS-CoV-2 variants to assess their impact on vaccine escape potential.

This study develops genome-wide lncRNA-derived SSR markers for Dongxiang wild rice and validates their polymorphism and utility in genetic diversity analysis and breeding.

The paper introduces a 4D subtractive manufacturing technique to create perfusable complex tissues in multi-well plates, enabling the fabrication of vascular networks and organ-specific structures.

The paper reports the discovery of a neutralizing nanobody, VHH60, effective against SARS-CoV-2 and its variants, with high potency and protective efficacy in mice.

This study shows that multiple neutralizing epitopes in SARS-CoV-2 spike proteins are targeted by polyclonal antibodies, and 20 mutations can confer resistance, but vaccinated and infected individuals' plasma neutralizes these resistant variants and diverse sarbecoviruses.

This study examines memory B cell evolution 5 months after mRNA vaccination in naive individuals, finding increased neutralizing activity but no further breadth or potency, and higher overall plasma neutralizing potency compared to natural infection.

This study tests if blocking mitophagy improves ethanol production in yeast used for fuel ethanol, finding no improvement in fermentation performance despite prior success in sake brewing.

This study identifies potent SARS-CoV-2 PLpro inhibitors through high-throughput screening and a FlipGFP-based assay, showing improved antiviral activity compared to existing compounds.