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Mapping fibrotic microenvironments: single-cell and spatial profiling of Schistosoma mansoni-induced tissue fibrosis

This study uses single-cell spatial transcriptomics to map fibrotic microenvironments in Schistosoma mansoni-infected mice, revealing organ-specific fibrosis architecture and shared signaling pairs for potential therapeutic targets.

Force-Enhanced Sensitive Detection of New DNA-Interactive Agents from Microorganisms at the Single-Molecule Level

This paper introduces a single-molecule stretching assay to detect DNA-intercalating agents from microorganisms, identifying two strains and three compounds with anti-cancer activity.

Promotion of tumor angiogenesis and growth induced by low-dose antineoplastic agents via bone-marrow-derived cells

This study investigates low-dose antineoplastic agents' effects on tumor growth and angiogenesis via bone-marrow-derived cells in mouse models.

Lymphotoxin-β Promotes Bone Colonization and Osteolytic Outgrowth of Indolent Bone Metastatic cells of Breast Cancer

This study identifies lymphotoxin-β as a key factor promoting bone colonization and osteolytic outgrowth of breast cancer metastatic cells.

CryoFIB milling large tissue samples for cryo-electron tomography

This paper introduces a cryoFIB milling workflow for isolating objects of interest from large tissue samples, resulting in thin lamellae suitable for cryo-electron tomography.

SOGO-SOFI, light-modulated super-resolution optical fluctuation imaging using only 20 raw frames for high-fidelity reconstruction

This paper introduces SOGO-SOFI, a light-modulated super-resolution imaging technique that uses only 20 frames for high-fidelity reconstruction, achieving higher temporal resolution and reduced artifacts compared to pcSOFI.

Repopulating Kupffer Cells Originate Directly from Hematopoietic Stem Cells

This study shows that repopulating Kupffer cells in adult mice originate directly from hematopoietic stem cells, not from preexisting Kupffer cells or monocytes.