Architecture of the human erythrocyte ankyrin-1 complex
F. Vallese, K. Kim, L. Y. Yen…·O. B. Clarke
This study presents structures of the human erythrocyte ankyrin-1 complex, revealing its architecture and interactions with membrane proteins.
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84 papers
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F. Vallese, K. Kim, L. Y. Yen…·O. B. Clarke
This study presents structures of the human erythrocyte ankyrin-1 complex, revealing its architecture and interactions with membrane proteins.
S. Abuhattum, P. Kotzbeck, R. Schluessler…·A. V. Taubenberger
This study investigates how adipocyte shape, size, and lipid accumulation affect mechanical properties of adipose tissue in health, obesity, and diabetes.
D. Kim, S. Gadad, R. Setlem…·W. L. Kraus
This study identifies lncRNA152 as an angiogenesis-inhibiting tumor suppressor in TNBC that upregulates RBM47, reducing cancer aggressiveness.
X. Bai, D. Verma, C. Garcia…·E. Chan
This study shows that cigarette smoke-exposed T regulatory cells impair macrophage control of Mycobacterium tuberculosis infection in vitro and in vivo.
K. Kim, P. Calabrese, S. Wang…·X. Chen
The paper shows host APOBEC3A, APOBEC1, and APOBEC3G edit SARS-CoV-2 RNA, promoting viral replication and suggesting APOBEC-mediated mutations contribute to viral evolution and new strain emergence.
Y.-E. Jung, K. W. Lee, J. H. Cho…·S.-S. Cha
This study investigates the thermal behavior of FGF21 and designs a variant with enhanced therapeutic potency through structural analysis and mutagenesis.
E. Thomson, M. Harfouche, P. Konda…·E. A. Naumann
The paper introduces a multi-camera array microscope (MCAM) that enables high-resolution, multi-scale imaging of behavior and neural activity in model organisms.
H. Shin, J. E. Park, H. R. Park…·J. H. Huh
This study investigates how genome divergence and compatibility contribute to the stabilization of hybrid genomes in an allopolyploid plant species.
G. Lee, H.-Y. Choi, W. Jo, K. Kim
This study evaluates stress levels in mice across different breeding environments, finding lower cortisol and higher body weight in individually ventilated cages with environmental enrichment.
E. N. Kim, J. Yu, J. S. Lim…·S. J. Oh
This study investigates mCRP deposition in AAA and identifies associated proteomic changes and enriched pathways.
G. Kim, D. Ahn, M. Kang…·Y. Park
This paper develops a framework for rapid bacterial species identification using 3D quantitative phase imaging and artificial neural networks, achieving 99.9% accuracy with single colony-forming units.
M. Gupta, C. M. Azumaya, M. Moritz…·K. I Pawar
The paper uses cryo-EM and AlphaFold2 to determine the structure of SARS-CoV-2 Nsp2, revealing its zinc-binding site and potential interactions with host proteins.
K. Kim, V. R. Gade, T. V. Kurzchalia, J. Guck
This study uses optical diffraction tomography to quantify structural and material changes in Caenorhabditis elegans dauer larvae during desiccation.
N. H. Cho, K. C. Cheveralls, A.-D. Brunner…·M. D. Leonetti
The paper maps human protein localization and interactions using genome engineering, imaging, and data science, revealing functional communities and RNA-binding protein subgroups.
Z. Melville, K. Kim, O. B. Clarke, A. R. Marks
The paper uses cryoEM to solve high-resolution structures of RyR1 in liposomes, achieving 3.36 and 3.98 Å resolution for closed and open states, respectively.
S.-H. Lee, J. S. No, K. Kim…·J.-W. Song
This study identifies two novel paramyxoviruses, PAPV-1 and PAPV-2, from Apodemus agrarius rodents in Korea, revealing distinct genome structures and zoonotic potential.
M. De Agrò, D. C. Roessler, K. Kim, P. S. Shamble
This study shows jumping spiders can distinguish biological from non-biological motion in point-light displays, but not between semi-rigid movements, similar to vertebrates.
J. MIAO, C. Wang, A. Lucky…·L. Cui
This study identifies a unique GCN5 histone acetyltransferase complex in Plasmodium falciparum that regulates erythrocyte invasion and virulence by modulating chromatin states and gene expression.
C. Roffay, G. Molinard, K. Kim…·A. Roux
This study quantifies how cell volume and membrane tension change during osmotic shocks and shows they are coupled but not entirely independent.
C. Y. Kim, M. Lee, S. Yang…·I. Lee
The paper expands the human gut microbiome reference database by incorporating newly assembled genomes from under-represented Asian populations, improving taxonomic and functional classification and revealing associations with autoimmunity.
R. Schlüssler, K. Kim, M. Nötzel…·J. Guck
This paper introduces FOB microscopy to measure sub-cellular density and mechanics with fluorescence specificity, revealing differences between nucleoplasm and cytoplasm.
P. M. McCall, K. Kim, M. Ruer-Gruss…·J. Brugues
This paper introduces a label-free method to measure the composition of biomolecular condensates with many components, showing it can capture complex dynamics and stoichiometry without perturbing the system.
J. Park, Y. R. Chung, S. T. Kong…·K.-H. Jung
This paper introduces metrics to group pathology cohorts for deep learning cancer diagnosis, balancing model count and performance without linearly increasing models with cohort numbers.
K. Kim, M. Vöröslakos, A. Fernandez-Ruiz…·E. Yoon
The paper introduces HectoSTAR microLED optoelectrodes for large-scale in vivo opto-electrophysiology, enabling high-precision extracellular recording and optical modulation of over 100 neuronal targets.
A. Wells, K. Grimes, K. Kim…·C. Coyne
This study shows that hFcRn and IFN signaling determine echovirus pathogenesis in mice, with hFcRn-IFNAR-/- mice modeling human disease.
D. Sharifi Kia, Y. Shen, T. N. Bachman…·M. A. Simon
This study examines how healthy aging affects right ventricular structure and biomechanical properties in rats, finding increased peak pressures, wall thickness, and fiber reorientation.
K. Kim, T. Moretti, S. Park, J. Kim
This study shows that CRL3KLHL12 and CRL3KLHL41 regulate the unfolded protein response by influencing COPII coat assembly and UPR sensors in different cell lines.
R. K. Singh, K. Kim, R. B. Rowswell-Turner…·R. Moore
This study shows that MeTC7, a VDR antagonist, reduces PD-L1 expression in cancer cells and inhibits neuroblastoma growth independently of PD-L1.
A. Gainullina, L.-H. Huang, H. Todorov…·ImmGen Consortium
The paper analyzes metabolic diversity in mononuclear phagocytes across tissues using integrated datasets and a network-based approach, identifying key metabolic subnetworks and their functional roles.