S. Roy

This paper introduces a multiview super-resolution microscopy approach that enhances confocal microscopy resolution and reduces phototoxicity across multiple scales.

This study presents a protocell model showing how functional diversification of ribozymes can drive evolutionary complexity in an RNA world.

This study compares the antioxidant and antibacterial activities of different extract fractions from Callistemon citrinus leaves, finding the aqueous fraction has highest antioxidant activity while petroleum ether has highest antibacterial activity.

This study shows that in vivo protein nitration and denitration in Vibrio cholerae under anaerobic conditions enhance cell survival by managing nitrite and nitrate levels.

This paper introduces a phylogenomic platform for angiosperms, providing a large dataset and open tool for exploring the flowering plant tree of life.

This study demonstrates that enhanced biological phosphorus removal (EBPR) can be stable at 35°C in lab-scale reactors, with nearly complete phosphorus removal and diverse PAO communities.

This study identifies a zygotene cilium in zebrafish oocytes that mechanically regulates chromosomal bouquet formation and germ cell morphogenesis, essential for fertility.

This paper introduces ELViM, a reaction coordinate-free method to analyze energy landscapes of IDPs, revealing conformational differences between phosphoforms of PAGE4.

This study identifies miR775 as a regulator of growth and development in Arabidopsis thaliana by targeting a β-(1,3)-galactosyltransferase, affecting rosette size and responding to UV-B and hypoxia.

The paper shows that reduced miR158 activity in Arabidopsis leads to 21-nucleotide tertiary phasiRNA generation targeting NHX2, affecting transpiration and stomatal conductance.

This study shows that Matriptase promotes tissue damage responses by activating Gq signaling, leading to RSK and DUOX activation, which disrupts epithelial junctions and contributes to inflammation and carcinoma.

The paper introduces a high-throughput phenotyping platform to measure multiple ion uptake rates in maize roots, revealing shared genetic mechanisms and heritable variation in nutrient uptake.

This study shows clerodin induces mitotic abnormalities, G2/M arrest, and polyploidy in cells, similar to colchicine, through microtubule destabilization and shared binding site interaction.

This study examines the effects of a petroleum ether fraction from Clerodendrum viscosum on cell cycle delay and metaphase arrest in A. cepa root tip cells.

This study shows that engineered FGF-1 (TTHX1114) reduces HSV-1-induced corneal disease in mice by increasing anti-inflammatory M2 macrophages and decreasing pro-inflammatory M1 macrophages.

This study identifies the GEMC1-MCIDAS transcriptional program as essential for multiciliogenesis in the choroid plexus and its role in preventing tumorigenesis.

The paper analyzes SARS-CoV-2 genome sequences from India to identify non-synonymous mutations and their functional implications, finding a higher prevalence of uracil substitutions and potential implications for antiviral drug design.

This paper shows that reducing disulfide bonds in ZIKV NS1 protein destabilizes its dimer structure, leading to asymmetry and reduced virulence.

The paper examines the evolutionary changes in GIV/Girdin's modularity, interactome, and functions across invertebrates and vertebrates, revealing distinct roles in cancer as tumor suppressor or oncogene.

The paper uses intravital imaging to show macrophage-induced cancer stem cells (CSCs) are enriched at TMEM doorways during metastasis, with CSCs comprising >60% of circulating tumor cells.

This paper develops a scalable platform for producing SARS-CoV-2 spike protein pseudotyped MLV-like particles, showing efficient incorporation of a truncated spike protein into VLPs.

This study shows that mutations in two FANC genes in mice model the severity and heterogeneity of Fanconi Anemia, revealing functional synergism of polygenic mutations.

This study identifies how receptor tyrosine kinases activate heterotrimeric G proteins through phosphorylation of Gi's interdomain cleft tyrosines, revealing a tyrosine-based signaling mechanism with implications in cancer.

This paper analyzes the dynamics of COVID-19 related publications across PubMed, Elsevier, and ResearchGate, finding rapid growth in publication rates and geographic author distribution.

This study shows that γH2AX peaks in S phase after UV irradiation due to replication activity, not DNA damage extent, and cells complete replication before arresting in G2.

The paper investigates denitrification kinetics and nitrous oxide (N2O) accumulation in Accumulibacter under different electron acceptor conditions, finding no effect of electron competition on N2O uptake.

This study identifies a dynamic conformational asymmetry in the 2019-nCoV spike protein that enhances its infectivity by enabling rapid recognition of host-cell receptors.

The paper reconstructs gene regulatory networks in cichlids to study GRN evolution linked to adaptive traits, identifying regulatory variants and network rewiring in visual opsin genes.

This study surveys the conservation community to assess their access to scientific literature, finding that about half struggle with access despite high demand.

The paper detects the mcr-1 gene in Salmonella isolates from poultry in Bangladesh using PCR and bioinformatics analysis, revealing colistin resistance mechanisms.