J. Zhou

This study develops an Omicron-specific mRNA vaccine that shows superior neutralizing antibody responses in mice, hamsters, and macaques compared to existing vaccines.

This study uses molecular dynamics simulations to analyze how different intervals between bipolar pulses affect phospholipid membrane electroporation, identifying three states and their dynamics.

This study uses molecular dynamics simulations to investigate how phospholipid composition and cholesterol content affect electroporation in lipid bilayers.

The paper presents a low-cost, open-source imaging and analysis system for automated nematode infection phenotyping in Arabidopsis thaliana.

This study identifies Carmn, a SMC-specific lncRNA, as critical for maintaining GI smooth muscle contractile function and motility, with loss of function leading to impaired contractility and pseudo-obstruction.

This paper predicts SARS-CoV-2 antigenic evolution using MLAEP, a deep learning model that identifies mutations associated with immune escape and validates them through experiments.

This study identifies keystone metabolites linking switchgrass rhizosphere metabolome and microbiome dynamics under nutrient and moisture stress.

This study combines transcriptome and metabolome analysis to identify molecular responses of Desmodesmus sp. to sewage treatment, revealing key pathways and metabolite changes.

This paper develops an integrative deep learning model combining image, clinical, and genomic data to improve risk stratification for colon adenocarcinoma patients, showing better performance than models using single data types.

This study investigates the role of fungal pectin methylesterases in ectomycorrhiza formation with Populus tremula x Populus tremuloides, finding that LbPME1 affects ECM development through pectin de-esterification.

The paper profiles autoantibodies in peritoneal fluids of women with endometriosis, identifying significant autoantibody prevalence and associations with infertility and disease mechanisms.

This study compares the antigenic properties of SARS-CoV-2 Omicron variants BA.4 and BA.5 with BA.1, BA.2, and vaccine-induced antibodies, finding they are antigenically distinct and show enhanced neutralisation breadth after breakthrough infection.

This study shows that amyloid fibrils form at the interface of hnRNPA1 condensates, not uniformly within them, and that surfactants can inhibit this process.

This paper identifies a new family of 'Ca. Nanohaloarchaeota' from hypersaline environments, showing they are an intermediate stage in the evolution of symbiosis with Halobacteria.

This study shows Delta and Omicron SARS-CoV-2 variants do not provide cross-protective immunity against reinfection in hamsters.

This study identifies distinct gut microbiome signatures in adult atopic dermatitis patients compared to healthy individuals in southern China.

The paper uses cell-type-specific transcriptomics to show how WCS417 affects root cell types, revealing roles for root hairs in immunity and endodermal barriers in beneficial association.

This study shows that hybrid immunity and vaccine boosters provide potent neutralizing activity against Omicron BA.1 and BA.2, while breakthrough infections induce nasal mucosal neutralization and identify an ultrapotent pan-variant antibody.

This study analyzes Usutu virus genomes to identify lineage-specific codon usage patterns and host adaptation mechanisms.

The paper identifies maternal and embryonic signaling-driven differentiation of luminal epithelial cells in the mouse endometrium and shows conservation in humans.

This study compares the transcriptomes of Geobacter metallireducens during DIET with different electron-accepting partners, showing varied gene expression and requirements for DIET.

This paper identifies a potent antibody cocktail that synergistically neutralizes SARS-CoV-2 and its variants, including Omicron BA.1 and BA.2.

This study develops a miniaturized ultrasound transducer for full-mouth oral health monitoring, demonstrating high-resolution imaging and accurate gingival thickness measurement.

The paper shows that hypoxia induced by pinewood nematode (PWN) loading increases tracheal elasticity and ECM thickness in beetles, enhancing PWN transmission.

This study shows that TSS inhibits the TLR3 pathway, reducing CVB3 infection severity in mice and cell cultures.

This study identifies a conserved mechanism by which pH-sensing regions regulate reversible amyloid formation in pyruvate kinase across yeast and human cells.

The paper identifies a novel role of the pyruvate dehydrogenase complex in regulating mitophagic selectivity independently of its enzymatic activity.

This study shows hyperuricemia induces renal tubular epithelial pyroptosis via ROS-mediated NLRP3 inflammasome activation in cultured cells and rat models.

This paper develops hetero-bivalent nanobodies that neutralize multiple SARS-CoV-2 variants, including Omicron, and show protective effects in vivo.