Y. Liu

This study shows that ketosis reduces AAA expansion and rupture by downregulating CCR2 and improving MMP balance in rat models.

The paper designs and evaluates synthetic isopentyldiol pathways in E. coli, finding that a computationally designed pathway produces IPDO at 2.2 mg/L from glucose.

This study shows that increasing HDAC6 activity impairs mitochondrial complex I in diabetic hearts subjected to ischemia/reperfusion, and that inhibiting HDAC6 improves cardiac function.

This study identifies miR-193a-5p as a regulator of vascular smooth muscle cell proliferation and migration in aortic aneurysms, showing that RelB represses its expression.

The paper develops a high-throughput platform for screening functional neo-antigens and their specific TCRs using droplet microfluidics and DNA barcoding.

This paper develops a finite element model of the chinchilla inner ear to study how CI electrode insertion angle affects residual hearing, finding minimal hearing loss with optimal angles.

This study identifies a FACT-ETS-1 antiviral pathway that restricts poxvirus replication and shows how viral A51R proteins counteract it.

The paper uses a CRISPR screen to identify TREX1 as a pro-viral host factor that modulates DNA sensing during influenza infection.

The paper was withdrawn due to the need for additional experimental evidence and reorganization of data and writing.

This study shows taurine biosynthesis via ADO enhances NST in inguinal adipose tissue by remodeling chromatin to increase gene transcription for thermogenesis.

The paper identifies four WRKY transcription factors upregulated by sugar via a superoxide signaling pathway dependent on hexokinase 1, suggesting a role in plant growth regulation.

This study shows that loss of WNT5A and WNT5B in mice protects against DSS-induced colitis by reprogramming spleen neutrophils to suppress inflammation.

The paper defines novel osteolineage gene sets using single-cell transcriptomics and identifies molecular defects in a CKD mouse model.

This study identifies new Bd lineages in China and finds sub-lethal effects on amphibians, supporting Asiatic origins of the pathogen.

This study identifies Cdc73 as a Notch cofactor that protects T-ALL cells from DNA damage and mitochondrial stress by intersecting with Notch at chromatin to activate oncogenes and repair pathways.

This study shows neuronal activity drives SCLC growth in both primary lung tumors and brain metastases through electrical and calcium signaling mechanisms.

The paper shows that P. aeruginosa HQNO induces S. aureus STX production, enhancing both pathogens' resistance to immune defenses in co-infections.

This study shows that COVID-19 vaccination enhances the activation and redistribution of CD16brightCD56dim NK cells in Omicron BA.2-infected patients, improving clinical outcomes.

Lon1 knockout inhibits mitochondrial-encoded gene translation and induces retrograde signaling involving unfolded protein responses.

The paper identifies Angptl4's role in shaping intrahepatic T-cell activation via eIF2α signaling during fibrosis in diet-induced NAFLD.

This study compares rule-learning strategies between humans and macaque monkeys in a card-sorting task, finding differences in speed and error patterns.

This study demonstrates that trisomy of chromosome 1q is essential for malignant growth in cancers and shows that TP53 mutations are mutually exclusive with 1q aneuploidy.

This study measures stable isotope fractionation in Bombyx mori strains across life stages to trace isotope movement and understand fractionation patterns.

The study investigates viral ecology in urban rodents during the COVID-19 pandemic, finding no SARS-CoV-2 infection but evidence of potential exposure through antibodies.

The paper shows that plants can distinguish between beneficial and pathogenic Pseudomonas fluorescens strains through distinct immune responses.

The paper identifies transcription factors driving distinct CD8+ T cell states and shows their impact on tumor control and immunotherapy.

This study shows YAP suppresses AR-driven prostate cancer growth by blocking TEAD-mediated AR signaling through competitive binding.

This study shows that peptide-poloxamine-DNA nanoparticles provide complete protection against lethal SARS-CoV-2 challenge through robust mucosal immunity.

This study develops a deep learning model to classify hematopoietic stem cells and multipotent progenitors using light microscopy images, demonstrating its effectiveness in distinguishing functional subpopulations.

The paper identifies SENP1 and Hippo signaling pathway activation as factors contributing to drug resistance in melanoma using transcriptomic and functional analyses.