H. Xu

This paper generates an acylsugar-deficient Nicotiana benthamiana mutant to improve studies of plant-insect interactions and virus transmission.

This study evaluates the efficacy and safety of combining ipratropium bromide and salbutamol in children and adolescents with asthma, finding reduced hospital admissions but no significant adverse event differences.

The paper develops deep learning algorithms to segment leaf vein networks and quantifies multi-scale architecture, revealing previously-undescribed variation across species.

The paper tests whether beta-diversity contributes to the latitudinal gradient in species richness by analyzing tree species data across East Asia.

This paper develops a rapid, low-cost method to detect and quantify SARS-CoV-2 virus particles using nanoplasmonic sensors in microplate readers and smartphone devices.

The paper discovers a high-magnesium calcite armor in leaf-cutter ants, showing it enhances exoskeleton hardness and protects against predation and fungal infection.

This paper proposes a model of Hsp90-mediated kinase client activation, suggesting ATP-driven conformational changes enable clients to reach their active state.

This study evaluates the toxicity of miR-874 antagomiR and miR-146a in cardiomyocytes and cardiac fibroblasts, finding no significant effects on caspase activity or Ca2+ levels but potential impacts on MMP9 expression.

This paper develops a bio-active scaffold combining HMGB1 and kartogenin to enhance meniscus healing, showing activation of stem cells and promotion of tissue repair in vitro and in vivo.

The paper presents a stochastic simulation platform that models transcriptional kinetics and estimates reaction rates using a Gillespie algorithm and single-cell RNA imaging data.

This study shows that laminin-511 and α6 integrins regulate CXCR4 expression to promote endothelial morphogenesis and tube integrity.

The paper develops a robust ChIP protocol that significantly improves enrichment fold in birch and Arabidopsis, and is applicable to both woody and herbaceous plants.

The paper investigates the genetic basis of rumen evolution by comparing transcriptomes and genomic data across ruminants, camels, and cetaceans, identifying key genetic innovations.

The paper identifies how TGF-β signaling inhibition allows GATA4 to interact with JMJD3, promoting cardiomyogenesis by demethylating H3K27me3 at cardiac gene promoters.

This study identifies an insertion sequence in SARS-CoV-2 spike protein that enhances cleavage efficiency and expands tissue tropism beyond the lungs.

This study identifies ACE2-expressing cells in the digestive system using single-cell transcriptomes, suggesting the digestive tract as a potential route for 2019-nCov infection.

This study develops a method to mature hiPSC-CMs, enabling them to model adult-onset cardiovascular disease like hypertrophic cardiomyopathy.

This paper presents a protocol for high-throughput immunofluorescence of suspension cells, enabling systematic protein localization analysis in hematopoietic cells.

This study identifies NMD-escape fs-indels as a biomarker associated with improved response to immunotherapy in melanoma patients.

This study constructs large-scale, morphologically controlled λ-DNA networks using a DC electric field and investigates factors affecting their structure.

This study shows that alpha 6 integrins regulate cytokinesis by controlling RSK2 and MKLP1 expression in salivary gland epithelial cells.

The paper develops a DIVA strategy using epitope-containing short peptides (ECSPs) to differentiate vaccinated from infected animals, showing distinct IgG serodynamics that enable effective monitoring.

This study shows that neogambogic acid inhibits osteosarcoma by targeting the USP9x/SOX2 axis through ubiquitin proteasome-mediated degradation of SOX2.

The paper demonstrates bioelectrical domain wall migration as a novel form of long-range signaling in tissues.

This study evaluates the prognostic role of c-Met overexpression in high-grade glioma through meta-analysis and finds it correlates with poor progression-free survival but not overall survival.

The paper quantifies intraspecific root and leaf trait variation across a tropical forest successional gradient and shows how this variation affects community-weighted trait patterns.

The paper uses shotgun metagenomics to analyze the gut microbiome in AS patients, finding enriched bacterial epitopes linked to HLA-B27 and effects of TNFi therapy and host genotype on microbiome composition.

This paper develops a 96-well platform of cardiac microtissues to measure contractile force for drug screening and tissue engineering.

This study investigates the effects of fasting caecotrophy on growth performance and lipid metabolism in rabbits using RNA-Seq, finding reduced body weight, lipid droplet accumulation, and altered gene expression related to lipid metabolism.

The paper shows that transcytosis helps maintain CFTR apical polarity by retrieving basolateral CFTR and counteracting missorting caused by mutations or loss of NHERF1 interaction.