J. Yan

This study presents the first de novo genome of Jasminum sambac and identifies gene clusters and pathways involved in flower fragrance biosynthesis.

This study shows that stretching forces trigger Ca2+ influx through L-type channels in filopodia, causing persistent Ca2+ oscillations that influence cell migration.

This study identifies a Krt5-BMP4 mechanosignaling pathway that regulates histone modifications and blastema cell remodeling during zebrafish heart regeneration.

This paper develops a rapid, sensitive, and low-cost nanozyme-based chemiluminescence paper test for SARS-CoV-2 antigen detection with results in under 16 minutes.

This study evaluates how different storage conditions, preservation periods, and sequencing platforms affect gut microbiome profiles using 16S rRNA gene sequencing.

This study shows cingulin regulates apical and tight junction membrane mechanics by organizing myosin-2B and gamma-actin and modulating ZO-1 conformation in MDCK cells.

This study identifies an optimized mRNA UTR combination (NASAR) that significantly enhances SARS-CoV-2 antigen expression in vitro and in vivo.

This study shows Parkin orchestrates mitochondrial lipid remodeling through phospholipase D2 and Lipin-1 to drive mitophagy via DAG production and autophagosome formation.

This study identifies a non-canonical histone acetyltransferase in CYC/TB1-like proteins that regulates plant architecture by modifying histone H3 and activating gene expression.

This study designs and evaluates TRAP-CSP fusion antigens as malaria vaccines, finding that those containing the CSP repeat region provide complete sterile protection in mice.

This study shows that vinculin loss in murine skin disrupts adherens junctions, leading to loss of bulge stem cell quiescence through impaired force generation and YAP1 retention.

This study identifies qKW9, a gene affecting maize kernel weight by regulating photosynthesis through C-to-U editing of NdhB.

This study identifies sex pheromone plasmids as a mechanism for disseminating linezolid-resistance in E. faecalis through plasmid transfer.

This paper identifies HMGA2 as a regulator of DNA supercoiling and replication fork stability, showing its protective role against DNA damage from topoisomerase poisons and its potential as a therapeutic marker in cancer.

This study investigates how a breast cancer GWAS variant may regulate immune cell gene expression in the tumor microenvironment, potentially affecting cancer progression.

The paper presents the genome of Aquilegia coerulea and shows extensive allele sharing and introgression among species, with a unique chromosome evolutionary history.

This study investigates how forces affect filopodia adhesion, showing that myosin IIA and formins are essential for force-dependent adhesion and substrate preference.

This study examines the longevity of dental restorations in geriatric and adult special needs patients over 15 years, finding median survival of 6.25 years and factors associated with restoration failure.

The paper shows that Shine-Dalgarno sequence accessibility affects N-terminal codon bias in E. coli by modulating translation initiation efficiency.

This study shows that force-dependent vinculin binding to α-catenin stabilizes adherens junctions and regulates cell-cell contact dynamics and collective cell behavior.

This study shows Vibrio cholerae uses its Type VI Secretion System to enhance zebrafish intestinal motility, displacing commensal bacteria without killing them.

This study shows that ZO-1 undergoes tension-dependent stretching and folding, which regulates the localization of its interactors and affects epithelial homeostasis.

This study shows that deleting the Myc super-enhancer region in mice reduces Myc expression and tumor susceptibility without overt phenotypes, suggesting therapeutic potential for targeting this element in cancer.