X. Yang

The paper identifies immune cell-adipocyte communication regulating thermogenic adipocyte transcription through single-cell analysis in mice.

This study uses STED nanoscopy with a new dye to visualize mitochondrial cristae dynamics in live cells at high resolution.

This study shows that β-synuclein reduces the cytotoxicity and seeding capacity of α-synuclein fibrils by increasing their dynamics without altering their core structure.

The paper reports the crystal structure and cryo-EM reconstruction of a constitutively active Drosophila Orai mutant, revealing the molecular mechanism of channel activation and Ca2+ permeation.

This study identifies TRIM21-SERPINB5 as a mechanism promoting radioresistance in nasopharyngeal carcinoma by repressing TP53 through GMPS degradation.

This study introduces SLHC-seq, a new targeted sequencing method that improves detection of pancreatic cancer by analyzing short mutant cfDNA fragments, enabling earlier diagnosis.

This study analyzes genome-wide divergence patterns in two incipient shorebird species with gene flow, finding distinct genomic regions associated with reproductive isolation and adaptation.

The paper examines geographic patterns of bacterioplankton in interconnected lakes of the Yangtze River Basin, finding that distance-decay relationships and stochastic processes dominate bacterial community assembly.

This study identifies O-GlcNAc transferase as a suppressor of hepatocyte necroptosis and liver fibrosis, using both human and mouse models.

This study shows that chive gnat adults prefer black substrates regardless of color hues, brightness, or ambient light conditions.

This study identifies SMARCB1 loss as critical for RMC survival and shows proteasome inhibition as a potential therapeutic strategy.

The paper demonstrates a strong positive biodiversity-productivity relationship in a subtropical forest experiment, showing increased productivity with species richness and complementary effects over time.

This study identifies gut bacteria, particularly Clostridiales, as a source of tacrolimus metabolism, producing less potent metabolites that may explain variable drug exposure after oral dosing.

The paper investigates how tensile and shear stresses affect E-cadherin levels during Drosophila embryo axis elongation, finding distinct impacts on adhesion.

This study identifies and analyzes DNA methyltransferase genes in cotton, showing their functional diversity and stress-specific expression patterns.

This paper identifies a GYS2/p53 negative feedback loop that suppresses tumor growth in HBV-related hepatocellular carcinoma by regulating glycogen metabolism and p53 activity.

This study shows that Bacillus cereus YL6 promotes growth of soybean, wheat, and Chinese cabbage by solubilizing phosphorus and producing plant hormones, while also colonizing plant roots.

The paper identifies the N-cadherin interactome in primary cardiomyocytes using proximity proteomics, revealing over 350 proteins, many unique to CDH2.

This study evaluates the GenoType MTBDRplus and MTBDRsl assays for detecting drug-resistant Mycobacterium tuberculosis in Beijing isolates, showing high sensitivity for rifampicin and INH resistance, and their potential as supplementary diagnostic tools.

This study differentiates dermal mesenchymal stem cells into vascular endothelial cells using endothelial cell line conditioned medium, showing high CD31 expression and angiogenic ability.

This study identifies novel roles of autoreactive B cells in RA through transcriptome profiling, revealing potential therapeutic targets and mechanisms.

The paper identifies CD25lowFOXP3+ T cells as a subset of regulatory T cells expanded in autoimmune diseases, characterized by FOXP3 demethylation and distinct functional features.