X. Zhu

The paper determines cryo-EM structures of MlaFEDB and reveals its phospholipid transport mechanism, identifying functional residues and providing insights for antimicrobial drug development.

This study examines how stomatal traits evolve from C3 to C4 photosynthesis in Flaveria species, finding a stepwise change with significant shifts in stomatal density and size.

The paper identifies potent SARS-CoV-2 neutralizing antibodies from a pre-pandemic human antibody library, showing high somatic hypermutation and specific binding to the spike protein.

This study identifies amino acids involved in substrate recognition by mitochondrial copper and phosphate transporters through evolutionary and functional analyses.

This study identifies the metabolic pathways regulated by c-GMP in tomato seedlings under salt stress, showing its role in enhancing salt tolerance through changes in gene expression and metabolic profiles.

The paper investigates how microtubules and Gαo-signaling regulate the preferential secretion of newly synthesized insulin granules in β cells, showing that their absence leads to increased secretion of older granules.

This study shows that glycyrrhizic acid improves cognitive function in aged mice by enhancing T and B cell proliferation and blood perfusion.

This study identifies a single amino acid mutation that determines the difference in neutralization ability of a cross-reactive antibody between SARS-CoV-2 and SARS-CoV.

The paper identifies IGHV3-53 as a common VH gene for SARS-CoV-2 neutralizing antibodies and determines its structural basis for binding the RBD.

This study identifies a potent SARS-CoV-2 neutralizing antibody that protects hamsters from infection and lung damage.

The paper identifies PRG2 and AQPEP as misexpressed in fetal membranes in placenta previa and percreta using RNA-Seq and immunofluorescence.

This study identifies Alectinib as an FDA-approved drug that inhibits SARS-CoV-2 nucleocapsid phosphorylation and viral replication in vitro by targeting host kinases.

The paper identifies a SARS-CoV-2 antibody that cross-neutralizes SARS-CoV by binding a conserved epitope and relies on avidity for neutralization.

This study identifies an alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 RBD, showing that longer CDR H3 can bind with different angles and interactions.

This study develops a modeling framework to explore directed evolution strategies for engineering complex microbial communities, identifying effective methods to enhance their stability and functionality.

This study shows microtubules regulate beta cell heterogeneity in insulin secretion by controlling secretion hot spots through spatiotemporal dynamics.

This study shows allergen-activated sensory neurons release Substance P, which activates CD301b+ dendritic cells to migrate to lymph nodes and initiate Th2 responses.

The paper shows that monounsaturated fatty acids (MUFA) are essential for B cell function and humoral immunity, with SCD-mediated MUFA production supporting early B cell development and germinal center formation.

This paper identifies a small-molecule inhibitor of influenza A HA stem fusion using a fluorescence polarization screen and validates its antiviral activity against multiple H1N1 and H5N1 strains.

This paper introduces a method for delivering cells to infarcted mouse hearts using echocardiography-guided percutaneous injection, showing improved cardiac function with repeated dosing.

The paper was withdrawn due to the authors no longer supporting some conclusions.

The paper reports the cryo-ET structure of the luminal ring of the Xenopus laevis nuclear pore complex and identifies key structural features confirmed by cryo-EM.

The paper presents a high-resolution cryo-EM structure of the Xenopus laevis nuclear pore complex cytoplasmic ring, revealing new structural features and interactions.

Structural study of a cross-reactive SARS antibody reveals a conserved epitope on the SARS-CoV-2 receptor-binding domain.

This study shows that intra-BM MSC transfusion restores the BM microenvironment, suppresses leukemia, and reprograms macrophages to reduce tumor burden.

This study compiles 1,635 metagenome-assembled genomes from 134 biogas reactor datasets to explore microbial diversity and functional traits in anaerobic digestion.

This study shows that hexaploidization in wheat enhances genetic recombination of the ancestral diploid genome, increasing evolutionary potential and aiding wheat's global spread.

The paper evaluates electroultrafiltration using PVA-CNT composite membranes for protein separation, finding temporary improvements in selectivity and sieving compared to conventional membranes.

The paper identifies essential residues in ATP11A for its expression and flippase activity through mutation analysis and functional assays.

This study investigates human tau isoform aggregation in Alzheimer's disease, showing 3R tau aggregates faster than 4R and identifies key domains for aggregation, while demonstrating the use of RT-QuIC to detect misfolded tau.