Author

Z. Ou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Assay:spatial transcriptomics· 3

Frequent Co-Authors

P. Ren· 4 shared D. Chen· 3 shared J. Li· 3 shared A. Chen· 2 shared G. Hu· 2 shared H. Liu· 2 shared H. Lu· 2 shared H. Wang· 2 shared

Activity by Year

2020-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

P. Ren

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Spatiotemporal transcriptomic profiling reveals the dynamic immunological landscape of alveolar echinococcosis

Z. Ou, L. Li, P. Ren, T. Zhou, F. He, J. Chen, H. Cai, X. Han, Y. Wu, J. Li, X. Li, Q. Tan, W. Li, Q. Chen, N. Zhang, , H. Yan

This study uses spatiotemporal transcriptomics to analyze immune dynamics in E. multilocularis infected mouse liver, identifying key immune cell roles and shifts in immune strategy during infection.

Advanced Science · Feb 22, 2025Peer-reviewedImmunology

Persistent lung inflammation and alveolar-bronchiolization due to Notch signaling dysregulation in SARS-CoV-2 infected hamster

C. Li, N. Xiao, W. Song, A. H.-C. Lam, F. Liu, X. Cui, Z. Ye, Y. Chen, P. Ren, J. Cai, A. C.-Y. Lee, H. Chen, Z. Ou, J. F.-W. Chan, K.-Y. Yuen, , A. J.-X. Zhang

This study shows SARS-CoV-2 infection in hamsters causes persistent lung inflammation and alveolar-bronchiolization linked to Notch signaling dysregulation and potential cancer risk.

bioRxiv · May 13, 2024 · PreprintMicrobiology

Sordarin bound eEF2 unlocks spontaneous forward and reverse translocation on CrPV IRES

Z. Ou, A. Petrov

The paper observes eEF2-mediated forward and reverse translocation of CrPV IRES using single-molecule ribosome analysis, showing sordarin stabilizes eEF2 to enable multiple translocation cycles.

bioRxiv · Mar 4, 2023Biochemistry

Single-nucleus RNA Sequencing and Spatial Transcriptomics Reveal the Immunological Microenvironment of Cervical Squamous Cell Carcinoma

Z. Ou, S. Lin, J. Qiu, W. Ding, P. Ren, D. Chen, J. Wang, Y. Tong, D. Wu, A. Chen, Y. Deng, M. Cheng, T. Peng, H. Lu, H. Yang, , P. Wu

This study uses snRNA-seq and Stereo-seq to analyze the immunological microenvironment of cervical squamous cell carcinoma, identifying immune cell clusters and their associations with tumor progression and patient survival.

bioRxiv · Dec 23, 2021Cancer Biology

Screening of cell-virus, cell-cell, gene-gene interactions among kingdoms of life at single cell resolution

D. Chen, Z. Ou, J. Zhu, P. Ding, H. Wang, L. Luo, X. Ding, T. Lan, W. Wu, Y. Yuan, W. Wu, J. Qiu, Y. Zhu, Y. Jia, Y. Wei, , H. Liu

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

bioRxiv · Aug 13, 2021 · PreprintCell Biology

Viral receptor profiles of masked palm civet revealed by single-cell transcriptomics

D. Chen, Z. Ou, H. Wang, Y. Zhang, J. Zhu, F. An, J. Xu, X. Ding, P. Ding, L. Luo, W. Wu, Q. Qin, Y. Wei, W. Zhao, Z. Lv, , Y. Hua

The paper uses single-cell transcriptomics to profile viral receptor expression in masked palm civets, identifying potential tissue tropisms for 132 viruses.

bioRxiv · Jul 20, 2021 · PreprintImmunology

Differential heating of metal nanostructures by radio frequencies: a theoretical study

N. J. Rommelfanger, Z. Ou, C. H. C. Keck, G. Hong

This study calculates the absorption of RF/microwave energy by metallic nanoparticles in biological tissues, finding that prolate spheroids offer better heating than spheres for hyperthermia.

bioRxiv · Mar 31, 2021 · PreprintBiophysics

Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants

Z. Ou, Z. Chen, Y. Zhao, H. Lu, W. Liu, W. Li, C. Geng, G. Hu, X. Wang, P. Ren, N. Liu, S. Zhu, L. Lu, J. Li

The paper identifies genetic signatures for classifying HPV16, 18, 52, and 58 variants into lineages/sublineages with high accuracy using publicly available genomes.

bioRxiv · Jul 30, 2020Evolutionary Biology