B. Yang

The paper shows that Par-3 and dynein mediate polarized endosome movement during asymmetric division, leading to Notch signaling asymmetry in daughter cells.

This study shows that blocking integrin αvβ8 on T cells enhances anti-tumor immunity in multiple syngeneic models and is effective even when tumor cells do not express the integrin.

This study shows that knocking down both miR-21 and CXCR4 inhibits glioma progression more effectively than single-targeted knockdown, by suppressing PI3K/AKT and Raf/MEK/ERK pathways.

This study identifies membraneless protein granules formed by RTK oncoproteins that activate RAS/MAPK signaling independently of lipid membranes in cancer.

This paper introduces an improved oblique plane microscope with enhanced resolution and usability, demonstrating its application in imaging various subcellular dynamics and challenging biological phenomena.

This paper reprograms the endogenous CRISPR-Cas10 system in Mycobacterium tuberculosis for efficient gene editing, RNA interference, and genome-wide screening, enabling functional genomics studies and drug/vaccine development.

The paper identifies ten genes in maize that drive antibiotic biosynthesis, revealing a resilient pathway critical for disease resistance.

This paper develops a yeast biosensor to detect chlorothalonil and heavy metals toxicity, showing improved sensitivity through optimized culture conditions and morphological, ROS, DNA, and caspase 3 activity analysis.

The paper develops a method to measure multiscale chromatin folding and nuclear structures in single cells, revealing cell-type-specific architectures and physical principles of chromatin organization.

This study traces the evolutionary origin of the Hippo pathway from unicellular ancestors and examines its oncogenic alterations in mammals.

This study shows that high light and elevated temperature reduce certain glucosinolates but increase health-promoting metabolites in kale varieties.

This study shows that the maize Gβ subunit controls both shoot meristem development and immune responses, with implications for optimizing growth and defense tradeoffs in crops.

This paper introduces an efficient method to clone TAL effector genes from Xanthomonas oryzae using Gibson assembly, significantly reducing the time required compared to traditional methods.

This study determines the structure of an E. coli transcription activation complex and shows that Crl stabilizes σS to activate transcription without DNA contact.

The paper reports the first detection of Telenomus remus parasitizing Spodoptera frugiperda eggs in South China and estimates natural parasitism rates.

This study analyzes TCR repertoires in RA patients and identifies clonal expansion and shared repertoires between EMT and Th17 cells, correlating TCR diversity with disease activity.

This study heterologously expresses Stlac2 from Setosphaeria turcica and demonstrates its ability to decolorize malachite green with high efficiency.

This paper introduces a computational hyperspectral imaging method that improves reconstruction precision in multicolor fluorescent imaging by using spatial constraints, validated with simulated and experimental data.

The paper demonstrates a strong positive biodiversity-productivity relationship in a subtropical forest experiment, showing increased productivity with species richness and complementary effects over time.

This study shows HCMV IE1 protein causes SOX2 loss in NPCs by trapping unphosphorylated STAT3 in the nucleus, leading to neurodevelopmental damage.

The paper quantifies how altering gene expression noise in yeast affects fitness, showing it can be beneficial or deleterious depending on average expression levels.

This paper introduces a high numerical aperture epi-illumination SPIM system for fast and high-resolution volumetric imaging of live cells and single-molecule super-resolution microscopy.

This study investigates the anticancer effects of HNPG on JEC cells, finding it inhibits proliferation, invasion, and metastasis by inactivating the Wnt/β-catenin pathway.

The paper identifies three ZmSWEET13 paralogs as essential for phloem loading in maize, showing their role in carbon allocation and agronomical traits.

This study identifies SWEET11 and SWEET15 as critical for seed filling in rice by analyzing their expression, localization, and function in knockout mutants.