Q. Su

The TEAIV model: Extending the standard TEIV model to account for viral budding ramp up

The paper extends the TEIV model to account for non-instantaneous viral budding, showing improved fit to SARS-CoV-2 viral load data using linear ramp-up dynamics.

Combined aerobic and resistance exercise training alters the spatial transcriptome of skeletal muscle in young adults

This study examines how combined aerobic and resistance exercise training affects the spatial transcriptome of skeletal muscle in young adults, identifying fiber type-specific gene expression changes and shifts in interstitial cell populations.

Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC

The paper introduces a sensitive fluorescent biosensor, ExRai-CKAR2, to study subcellular PKC activity and finds differential regulation of PKC isoforms at the ER, lysosomes, and Par complexes.

Unbiased Complete Estimation of Chloroplast Number in Plant Cells Using Deep Learning Methods

This paper introduces a deep learning method for accurate 3D chloroplast counting in plant cells, achieving over 95% accuracy compared to manual methods.

Hormonal and transcriptomic analysis reveals the role of ABA and BR in breaking the barrier of inter-subgeneric hybridization in water lily (Nymphaea)

This study identifies ABA and BR as key regulators in overcoming inter-subgeneric hybridization barriers in water lily through transcriptomic and hormonal analyses.

Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Material From Neighboring Cells Using Intracellular Monitoring - a Novel Mechanism of Antigen Acquisition

Dendritic cells maintain RNA and protein levels for conditionally deleted genes by siphoning material from neighboring cells using a novel mechanism.

Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis

A Novel ARNT-Dependent HIF-2α Signaling as a Protective Mechanism for Cardiac Microvascular Barrier Integrity and Heart Function Post-Myocardial Infarction

This study identifies HIF2/ARNT as a protective axis in cardiac endothelial cells post-MI, preventing vascular leakage and inflammation through suppression of IL6.

Diet outweighs genetics in shaping gut microbiomes in Asian honeybee

This study shows that diet, particularly pollen polysaccharides, has a greater impact on shaping gut microbiomes in Asian honeybees than genetics.

Amplicon sequencing of single-copy protein-coding genes reveals accurate diversity for sequence-discrete microbiome populations

This paper develops a pipeline to identify single-copy protein-coding genes for accurately quantifying sequence-discrete populations in microbial communities, validated using Gilliamella in honeybee guts.

On the origin and evolution of Drosophila new genes during spermatogenesis

The paper analyzes single-cell transcriptome data to show that new genes in Drosophila testis show expression shifts and chromosomal distribution patterns consistent with meiotic sex chromosome inactivation.

Evidence for the Presence of Hyphae and Fruiting Body Calcium Oxalate Crystallites in Schizophyllum commune

The paper examines S. commune fruiting bodies and hyphae to confirm the presence of calcium oxalate crystallites, demonstrating biomineralization in this fungus.

Cryo-EM structures of human TMEM120A and TMEM120B

The paper reports cryo-EM structures of human TMEM120A and TMEM120B, revealing similar dimeric assemblies but no structural basis for their differing mechanosensing properties.

Honeybee genetics shape the strain-level structure of gut microbiota in social transmission

This study shows that honeybee genetics influence gut microbiota composition and strain-level diversity through social transmission, revealing a gut-brain connection.

Integrative Analysis the characterization of peroxiredoxins in pan-cancer

This study systematically analyzes peroxiredoxins (PRDXs) across 33 cancer types, examining expression, genetic alterations, methylation, prognosis, pathways, and drug targets, with validation of PRDX6's role in bladder cancer cell proliferation via JAK2-STAT3 pathway.

Recombinant SARS-CoV-2 RBD molecule with a T helper epitope as a built in adjuvant induces strong neutralization antibody response

This study develops a recombinant SARS-CoV-2 RBD molecule fused with a T helper epitope as an adjuvant, showing strong neutralizing antibody response in mice.

Complex plant metabolomes guide fitness-relevant foraging decisions of a specialist herbivore

This study shows how western corn rootworm integrates sugar and benzoxazinoid cues for foraging, with sugars aiding host finding and benzoxazinoids influencing acceptance, both improving growth and survival.

An enormous Paris polyphylla genome sheds light on genome size evolution and polyphyllin biogenesis

This study reports the largest sequenced plant genome, Paris polyphylla var. yunnanensis, and identifies genes involved in polyphyllin biosynthesis.

Establishing cell-intrinsic limitations in cell cycle progression controls graft growth and promotes differentiation of pancreatic endocrine cells

The paper investigates how limitations in S-phase progression affect pancreatic endocrine differentiation and graft growth, finding that impaired DNA replication enhances differentiation and prevents cystic growth.

Molecular basis for regulation of human potassium chloride cotransporters

This study presents the structures of human KCC2 and KCC3, including phosphorylation and inhibitor-bound forms, revealing mechanisms of regulation and potential drug targets.

Long-term absence of Langerhans cells alters the gene expression profile of keratinocytes and dendritic epidermal T cells

This study shows that long-term absence of Langerhans cells alters gene expression in keratinocytes and dendritic epidermal T cells, suggesting immune cells influence tissue homeostasis.