Author
S. Das
University of HyderabadPrimary ORCID profile (0009-0002-1975-4358 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2017-2026 · peak 32/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links149 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
Chlorpyrifos degradation by combined solar photo-Fenton and bacterial metabolism and simultaneous toxicity analysis in zebrafish (Danio rerio)
T. Nayak, A. Ghosh, S. Das…·V. Raina
This study evaluates the combined solar photo-Fenton and bacterial degradation of chlorpyrifos in wastewater and assesses its toxicity to zebrafish.
DOI 10.1101/2022.01.13.476273 - Cell BiologybioRxivPreprint
Transient interactions drive the lateral clustering of Cadherin-23 on membrane
C. S. Srinivas, G. S. Singaraju, V. Kaur…·S. Rakshit
This study shows that transient hydrophobic interactions drive lateral clustering of cadherin-23 on membranes, enhancing cell adhesion without requiring specific cis-dimer interactions.
DOI 10.1101/2022.01.09.475209 - MicrobiologybioRxiv
RG203KR mutations in SARS-CoV-2 Nucleocapsid: Assessing the impact using Virus-like particle model system
H. Raheja, S. Das, A. Banerjee…·S. Das
The paper assesses the impact of RG203KR mutation in SARS-CoV-2 nucleocapsid using virus-like particles, showing enhanced immune responses and neutralization.
DOI 10.1128/spectrum.00781-22 - MicrobiologybioRxivPreprint
Macrophage cell lines and murine infection by Salmonella Typhi L-form bacteria
S. Das, D. Ganguli, S. Chakraborty…·A. Gope
This study shows that antibiotic treatment of Salmonella Typhi can generate L-form bacteria that infect macrophages and mice, suggesting a mechanism for antibiotic resistance and disease transmission.
- Plant BiologybioRxivPreprint
Effect of growth forms of bamboo on the mycorrhizal and fluorescent pseudomonas population
S. Das, Y. P. Singh, Y. K. Negi, P. C. Shrivastav
The paper examines how different growth forms of bamboo affect mycorrhizal fungi and fluorescent pseudomonas populations in their rhizosphere.
DOI 10.1101/2021.12.08.471877 - ImmunologybioRxiv
Endowing Universal CAR T-cell with Immune-Evasive Properties using TALEN-Gene Editing.
S. Jo, S. Das, A. Williams…·J. Valton
This paper develops a novel CAR T-cell scaffold with immune-evasive properties to enable universal allogeneic CAR T-cell therapy.
DOI 10.1038/s41467-022-30896-2 - ImmunologybioRxiv
Neutralization Fingerprinting Technology for Characterizing Polyclonal Antibody Responses to Dengue Vaccines
N. Raju, X. Zhan, S. Das…·I. Georgiev
This study presents a computational framework to analyze neutralizing antibody specificities in response to dengue vaccines, revealing differences in immune responses based on prior infection status.
DOI 10.1016/j.celrep.2022.111807 - ImmunologybioRxiv
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis
S. Sinha, V. Castillo, C. R. Espinoza…·P. Ghosh
This study identifies shared cellular and molecular features between severe COVID-19 and idiopathic pulmonary fibrosis, highlighting ER stress and AT2 cell dysfunction as key drivers.
- Cell BiologybioRxiv
Tubular lysosome induction couples animal starvation to healthy aging
T. V. Villalobos, B. Ghosh, S. Alam…·A. E. Johnson
The paper shows that inducing tubular lysosomes through dietary restriction or mTOR inhibition links reduced food intake to lifespan extension in C. elegans.
DOI 10.1038/s43587-023-00470-6 - Evolutionary BiologybioRxiv
Density-dependent selection in Drosophila: evolution of egg size and hatching time
S. Venkitachalam, S. Das, A. Deep, A. Joshi
This study shows that egg size and hatching time evolve in response to different larval crowding regimes in Drosophila, with egg size consistently correlating with increased competitive ability.
DOI 10.1007/s12041-021-01355-6 - Cell BiologybioRxiv
Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs (tDRs)
G. Li, A. Manning, A. Bagi…·S. Das
The paper identifies distinct extracellular tRNA-derived small RNA (tDR) fragmentation signatures associated with different stress responses and shows their potential as biomarkers in human disease.
- Animal Behavior & CognitionbioRxivPreprint
The art of snacking: Innovative food extraction in a synanthropic species is associated with food exposure and food categorization
T. Dhananjaya, S. Das, A. K. Vyas…·M. Singh
The study examines how exposure and food categorization influence extraction methods in urban macaques when dealing with processed food.
DOI 10.1101/2021.09.01.458608 - Cell BiologybioRxiv
Role of miR-181c in Diet-Induced Obesity Through Regulation of Lipid Synthesis in Liver
K. Akiyoshi, G. J. Boersma, M. D. Johnson…·S. Das
This study investigates miR-181c's role in diet-induced obesity by showing its regulation of lipid synthesis in liver and its impact on metabolic parameters.
DOI 10.1371/journal.pone.0256973 - BioengineeringbioRxiv
Size dependent regeneration capacity of functionalized Capra ear derived micro-tissue scaffolds for treatment of cartilage defects
P. Maity, S. Mukherjee, M. Mandal…·S. Dhara
This study evaluates the regeneration capacity of size-dependent micro-tissue scaffolds derived from Capra ear cartilage for cartilage defect treatment in rabbits.
DOI 10.1016/j.mtla.2022.101569 - Cancer BiologybioRxivPreprint
Regulation of DNA damage response by trimeric G-protein Signaling
A. A. Abd El-Hafeez, N. Sun, A. Chakraborty…·P. Ghosh
This paper shows that GIV/Girdin modulates DNA damage response by suppressing HR and promoting NHEJ through BRCA1 sequestration and Akt pathway activation.
DOI 10.1101/2021.07.21.452842 - BiochemistrybioRxiv
Zinc2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro.
L. Panchariya, W. A. Khan, S. Kuila…·A. Arulandu
This study shows that zinc ions inhibit SARS-CoV-2 main protease and viral replication in vitro, with structural evidence supporting the mechanism.
DOI 10.1039/d1cc03563k - BioengineeringbioRxiv
Genetically engineered insects with sex-selection and genetic incompatibility enable population suppression
A. Upadhyay, N. Feltman, A. Sychla…·M. Smanski
The paper demonstrates a genetically engineered insect system using sex-selection and genetic incompatibility for population suppression in Drosophila melanogaster.
DOI 10.7554/elife.71230 - MicrobiologybioRxiv
The interaction of enteric bacterial effectors with the host engulfment pathway control innate immune responses
I. M. Sayed, S.-R. Ibeawuchi, D. Lie…·S. Das
The paper investigates how WxxxE bacterial effectors interact with ELMO1 to regulate inflammation, showing that ELMO1 differentiates pathogenic from commensal bacteria and enhances inflammatory responses through these interactions.
DOI 10.1080/19490976.2021.1991776 - ImmunologybioRxiv
Lung epithelial signaling mediates early vaccine-induced CD4+ T cell activation and Mtb control
S. Das, N. D. Marin, E. Esaulova…·S. A. Khader
This study identifies lung epithelial signaling as critical for early vaccine-induced CD4+ T cell activation and Mtb control in BCG vaccinated hosts.
DOI 10.1128/mbio.01468-21 - PhysiologybioRxiv
Genetic Inhibition of Serum Glucocorticoid Kinase 1 Prevents Obesity-related Atrial Fibrillation
A. Bapat, G. Li, L. Xiao…·D. Milan
This study shows that genetic inhibition of SGK1 reduces obesity-related atrial fibrillation in mice by decreasing fibrosis, inflammation, and altering electrophysiology.
DOI 10.1172/jci.insight.160885 - MicrobiologybioRxiv
Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen
S. Saul, M. Karim, P.-T. Huang…·S. Einav
This study identifies lapatinib, an ErbB inhibitor, as a broad-spectrum antiviral that suppresses SARS-CoV-2 and VEEV replication, inflammation, and lung injury through ErbB-mediated mechanisms.
- Cell BiologybioRxivPreprint
SPT6 loss Permits the Transdifferentiation of Keratinocytes into an Intestinal Fate that Recapitulates Barrett's Metaplasia
D. Vo, M. R. Fuller, C. Tindle…·P. Ghosh
The paper shows that SPT6 loss in keratinocytes leads to transdifferentiation into an intestinal fate, mimicking Barrett's metaplasia and linking acid exposure to metaplastic progression.
DOI 10.1101/2021.05.06.442930 - MicrobiologybioRxivPreprint
Optimized Quantification of Intrahost Viral Diversity in SARS-CoV-2 and Influenza Virus Sequence Data
A. Roder, K. E. Johnson, M. Knoll…·E. Ghedin
This study evaluates variant calling tools for detecting minority variants in viral sequencing data and provides guidance for accurate quantification of intrahost viral diversity.
DOI 10.1101/2021.05.05.442873 - MicrobiologybioRxiv
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
G. Shi, A. I. Chiramel, K. K. Lai…·A. A. Compton
This study shows rapalogs like rapamycin increase SARS-CoV-2 infection by reducing antiviral proteins through microautophagy, while ridaforolimus has less effect.
DOI 10.1172/jci160766 - ImmunologybioRxivPreprint
An AI-guided signature reveals the nature of the shared proximal pathways of host immune response in MIS-C and Kawasaki disease
D. Sahoo, G. Dattatray, C. Shimizu…·P. Ghosh
The paper identifies shared and divergent immune pathways in MIS-C and Kawasaki disease using gene signatures and clinical data.
DOI 10.1101/2021.04.11.439347 - PathologybioRxiv
Deep learning from multiple experts improves identification of amyloid neuropathologies
D. R. Wong, Z. Tang, N. C. Mew…·M. J. Keiser
The paper develops a deep learning model that combines multiple expert annotations to improve the identification of amyloid neuropathologies, achieving consistent diagnoses across varying expert opinions.
DOI 10.1186/s40478-022-01365-0 - ImmunologybioRxiv
Effect of chronic JUUL aerosol inhalation on inflammatory states of the brain, lung, heart and colon in mice
A. Moshensky, C. Brand, H. Alhaddad…·L. E. Crotty Alexander
Chronic JUUL aerosol inhalation in mice alters inflammatory states in brain, lung, heart, and colon, with flavor-dependent effects and potential long-term health risks.
DOI 10.7554/elife.67621