This paper identifies and characterizes the gene PLATZ-A1 underlying the GA-sensitive dwarfing locus RHT25 in wheat, showing it interacts with RHT1 and can modulate plant height.

bioRxiv · Jan 5, 2023 · PreprintPlant Biology

Prediction of range expansion and estimation of dispersal routes of water deer (Hydropotes inermis) in the transboundary region between China, the Russian Far East and the Korean Peninsula

Y. Li, Y. PENG, Y. MO, H. LEE, H. LI, W. ZHU, Y. DARMAN, D. K. LEE, T. WANG, G. SEDASH, P. PANDEY, A. BORZEE

This study predicts water deer range expansion and dispersal routes in Northeast Asia using MaxEnt and circuitscape, identifying key habitats and potential conservation corridors.

bioRxiv · Feb 16, 2022Ecology

Regulation of osteoblast autophagy based on PI3K/AKT/mTOR signaling pathway study on the effect of β-ecdysterone on fracture healing

Y. Tang, Y. Mo, D. Xin, Z. Xiong, L. Zeng, G. Luo

This study investigates how β-ecdysterone affects fracture healing by modulating autophagy via the PI3K/AKT/mTOR pathway in osteoblasts.

bioRxiv · May 28, 2021Animal Behavior & Cognition

Structured illumination microscopy artifacts caused by illumination scattering

Y. Mo, F. Feng, H. Mao, J. Fan, L. Chen

This study investigates SIM artifacts caused by light scattering in thick samples and shows how sample thickness affects 2D-SIM image reconstruction.

bioRxiv · Jan 1, 2021Biophysics

An Engineered Genetic Circuit for Lactose Intolerance Alleviation Coupled with Gut Microbiota Recovery

M. Cheng, Z. Cheng, Y. Yu, W. Liu, R. Li, Z. Guo, J. Qin, Z. Zeng, L. Di, Y. Mo, C. Pan, Y. Liang, J. Li, Y.-G. Tong, Y. Yan, , K. Ning

This paper presents a genetic circuit that alleviates lactose intolerance by boosting beta-galactosidase activity and restoring gut microbiota through pH regulation in mice.

bioRxiv · Sep 15, 2020 · PreprintBioengineering

Selective Activation of TASK-3-containing K+ Channels Reveals Their Therapeutic Potentials in Analgesia

P. Liao, Y. Qiu, Y. Mo, J. Fu, Z. Song, L. Huang, S. Bai, Y. Wang, J. J. Zhu, F. Tian, Z. Chen, N. Pan, E. Y. Sun, L. Yang, X. Lan, , H. Yang

The paper identifies CHET3, a selective TASK-3 activator, and demonstrates its analgesic effects in pain models, highlighting TASK-3 as a novel non-opioid analgesic target.

bioRxiv · Jun 28, 2019 · PreprintPharmacology & Toxicology

JNK-IN-8, a c-Jun N-terminal kinase inhibitor, improves functional recovery through suppressing neuroinflammation in ischemic stroke

W. Geng, H. Tang, Q. Dai, W. Hong, K. Han, D. Jia, Y. Mo, Y. Lv, H. Fu, J. Zheng

This study shows JNK-IN-8 improves functional recovery in ischemic stroke by reducing neuroinflammation through the JNK/NF-κB pathway.

bioRxiv · Oct 21, 2018Cancer Biology