L. Liao

Unravelling an Efficient O2/Reductant-Dependent Catalytic Route in Heme Peroxygenases for Sustainable Applications

This paper identifies an O2/reductant-dependent catalytic pathway in heme peroxygenases that avoids H2O2-induced inactivation, enabling efficient and sustainable chemical transformations.

Identification of a Novel Ferroptosis Inducer with Dual Modulatory Effects on GPX4 Activity and Stability

This study identifies MI-2, a novel GPX4 inhibitor that induces ferroptosis by inhibiting GPX4 activity and promoting its degradation, showing synergistic effects with existing cancer drugs.

Cyclic di-GMP interact with putrescine via a PilZ domain receptor YcgR

This study shows that c-di-GMP interacts with putrescine via the YcgR receptor to regulate bacterial motility in Dickeya oryzea, with c-di-GMP inhibiting putrescine's effect.

Immortalized bovine satellite cells for cultured meat applications

This paper develops genetically immortalized bovine satellite cells for cultured meat production, achieving over 120 doublings while maintaining myogenic differentiation capacity.

Targeting of plasmodesmal proteins requires unconventional signals

The paper identifies novel unconventional targeting signals in PDLP5 and related proteins that mediate plasmodesmal localization and function.

High-throughput tandem-microwell assay for ammonia repositions FDA-Approved drugs to Helicobacter pylori infection

This study identifies FDA-approved drugs that inhibit urease activity in H. pylori, offering potential new treatments for infections.

Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis

This study evaluates givinostat's efficacy in treating NASH by reducing inflammation and fibrosis in mouse models.

One New Species of the Genus Dryomys (Rodentia, Glirgae) from Xinjiang China, Dryomys Yarkandensis sp. nov

The paper describes a new species of rodent, Dryomys yarkandensis, discovered in Xinjiang, China, and compares it to other Dryomys species based on morphological characteristics.

Global gene expression profile during low temperature in the brain of grass carp (Ctenopharyngodon idellus)

This study investigates the transcriptome changes in grass carp brains under low temperature, identifying key pathways and genes involved in cold acclimation.

WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death

This study identifies WDR45's role in neurodegeneration by showing its regulation of ER homeostasis and neuronal death through autophagy defects.