B. Liu

The paper uses advanced microscopy techniques to characterize the structure of phagocytic podosomes during frustrated phagocytosis, revealing their unique actin architecture and associated protein distributions.

This paper shows that teicoplanin inhibits SARS-CoV-2 cell entry by blocking cathepsin L proteolytic activity, effective against multiple variants with IC50 values of 2.038 M and 2.116 M.

The paper investigates N2O emissions in two agricultural soils by analyzing denitrifying bacterial communities and their metabolic phenotypes, finding that differences in bacterial composition and gene function drive variations in N2O accumulation.

This study shows that Octopus chierchiae has unique, stable stripe patterns that can be used for photo-identification of individuals over time.

This paper reports chromosome-level genome assemblies of five Sitopsis species and identifies the B-subgenome donor of bread wheat as an extinct species closely related to Ae. speltoides.

This paper develops a chimpanzee adenovirus-based vaccine against the SARS-CoV-2 Delta variant and shows it induces strong immunity and protects mice from challenge.

This study develops a FLIM biosensor using merocyanine dyes to detect conformational changes in Cdc42, showing improved sensitivity at low activation levels compared to FRET-based methods.

The paper investigates the role of CmNAC-NOR in melon ripening by analyzing CRISPR/Cas9 mutants, finding that its disruption blocks climacteric ripening and alters fruit characteristics.

This study identifies STK25 as a kinase that phosphorylates PRKAR1A, inhibiting PKA signaling and reducing myocardial contractility in response to beta adrenergic stimulation.

The paper develops models to explain how force affects TCR signaling and antigen discrimination by analyzing bond characteristics of TCR-pMHC interactions.

The paper shows lung and other tissues produce prostacyclin via fibroblasts, providing systemic anti-thrombotic protection, challenging the traditional view that endothelium is the main source.

This study investigates how homoeologous exchange affects gene expression and alternative splicing in synthetic allotetraploid wheat, finding cis- and trans-regulatory impacts on gene expression and AS events.

This study shows that increased temperatures disrupt meiotic stability in autotetraploid Arabidopsis by interfering with chromosome pairing and crossing-over.

The paper identifies a cellular pathway involving Importin alpha-4 and Virp1 that facilitates nuclear import of noncoding RNAs, including viroids and a subviral satellite RNA.

This study shows that loss of endothelial PHD2 causes cardiac hypertrophy and fibrosis via HIF-2, and PHD2 is reduced in human cardiomyopathy.

This paper introduces two new methods for species tree inference under the multi-species coalescent model that use external constraints and are faster than existing methods.

The paper identifies ER-LBD, a novel estrogen receptor alpha isoform, which promotes breast cancer growth and resistance to endocrine therapy.

This study shows that extracellular fluid flow reduces cellular quiescence depth through physical and biochemical cues, making cells more likely to reenter the cell cycle.

This study shows that combining MPLA and IFNγ reprograms macrophages to kill cancer cells and reduce metastasis in breast and ovarian cancer models.

This study shows TET1 facilitates DNA demethylation of the Cxcl1 promoter, enabling its induction and neutrophil recruitment during acute lung injury.

The paper develops a fluorescent reporter system to measure bacterial cell division rates in vivo and finds that NO stress reduces division rates in Y. pseudotuberculosis within mouse spleens.

This paper develops a prediction system to reduce fungicide applications for controlling strawberry powdery mildew by timing sprays based on environmental conditions and disease progression.

This study shows that certain fatty acid binding proteins (FABPs) modulate glucocorticoid receptor (GR) transcriptional activity in a ligand-dependent manner, potentially enabling more targeted GR-based therapies.

This study identifies SARS-CoV-2 ORF8 as a protein that downregulates MHC-I to evade immune detection by promoting lysosomal degradation, reducing CTL-mediated cell elimination.

Conditional Tfr1 ablation in satellite cells causes ferroptosis, leading to skeletal muscle regeneration defects and labile iron accumulation, recapitulated in aged rodents.

This study investigates how high temperatures affect meiosis in autotetraploid Arabidopsis thaliana, revealing that heat stress disrupts chromosome axis stability and meiotic recombination.

The paper identifies PKMYT1 as a therapeutic target for CCNE1-amplified cancers, showing that its inhibition leads to synthetic lethality and tumor regression in combination with gemcitabine.

This study identifies and validates SARS-CoV-2 CD8+ T cell epitopes, demonstrates their cross-presentation, and shows the efficacy of peptide vaccines in transgenic mice.

The paper identifies PHAROH, an lncRNA overexpressed in hepatocellular carcinoma, which regulates c-Myc translation by sequestering TIAR, impacting cell proliferation and migration.