S. Xu

The paper investigates how media composition affects antibiotic susceptibility in E. coli using transcriptomics and machine learning, identifying key regulators and shifts in respiration and iron availability.

This study identifies Rab18's role in lipid droplet dynamics by showing it binds PLIN2 and ACSL3, promoting TAG accumulation and LD growth in muscle cells.

This study identifies HK2 as a marker for detecting underrepresented CTCs in NSCLC, revealing a distinct subpopulation with unique characteristics.

The paper identifies allelic differences in terpene synthase genes that contribute to correlated variation in herbivory-induced and floral volatiles in wild tobacco.

The paper identifies noncoding RNA-encoded proteins on lipid droplets, discovering LDANP1 which modulates lipid metabolism and insulin sensitivity.

The paper uses mathematical models and focus reduction assays to show that influenza virus neutralization and antibody consumption can lead to bistable growth kinetics, explaining reinfection and vaccine efficacy.

The paper uses cryo-EM to reveal the post-fusion structure of SARS-CoV-2, showing the S protein in a state with S1 disassociated.

This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.

This study shows that intra-BM MSC transfusion restores the BM microenvironment, suppresses leukemia, and reprograms macrophages to reduce tumor burden.

This study shows that exosomes from SVV-infected cells can carry and transmit SVV between susceptible and non-susceptible cells, and this transmission is resistant to neutralizing antibodies.

This study demonstrates that AGX51, an Id antagonist, effectively inhibits tumor growth in multiple cancer models without inducing acquired resistance.

The paper introduces iSCAPE, a system that separates atmospheric particles using electrostatic fields and mineral oil, showing different particle mobility and enrichment based on source and charge.

The paper identifies ACPT gene inactivation in toothless and enamel-less mammals and estimates its inactivation times across different lineages.

This study shows that loss of Tjp2 in hepatocytes and cholangiocytes leads to cholestatic liver disease and increased susceptibility to liver injury, with protective roles in regulating bile acid transporters and detoxification enzymes.

This study shows gut bacteria enhance dsRNA-induced mortality in leaf beetles by accelerating dsRNA degradation and causing microbiota dysbiosis.

This meta-analysis evaluates carbon nanoparticles' effectiveness in improving lymph node detection and protecting parathyroid glands during thyroidectomy, finding increased lymph node harvest and reduced parathyroid complications.

The paper reanalyzes experimental data to show that action potential propagation delays are small compared to signal duration, suggesting a new physical model for neural signal communication.

This study identifies the genetic basis for the evolution of a novel floral scent in wild tobacco, showing how gene expression changes lead to adaptive volatile compound production.

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

This study conducts a meta-analysis showing opioids increase fracture risk by 78% in patients with chronic noncancer pain.

The paper identifies a novel plant-specific TRAPP complex component, TRIPP, and shows its role in plant development through proteomic and genetic analyses in Arabidopsis.

This study evolves E. coli under acid stress and identifies genetic and expression changes that enhance acid tolerance.

This study uses TurboID to identify protein interactions and cell type-specific organellar proteomes in Arabidopsis, revealing novel interactors of a transcription factor and subcellular proteomes.

This study examines the evolution of the glutathione S-transferase gene family in cetaceans, finding lineage-specific gene losses and positive selection, suggesting adaptation to aquatic environments.

This paper investigates how Prototheca zopfii genotype II causes mitochondrial apoptosis and inflammation in bovine mastitis models.

This study identifies and characterizes a novel pic gene cluster in Alcaligenes faecalis JQ135 responsible for complete picolinic acid degradation into the tricarboxylic acid cycle.

This study identifies E-cadherin's role in suppressing sarcoma growth through both signaling (inhibiting p-CREB and TBX2) and mechanical (enhancing cell-cell adhesion) mechanisms.

This paper uses NMR to determine how P[8] and P[6] rotavirus VP8* domains bind to different histo-blood group antigens, revealing structural differences that may explain their distinct host ranges and evolutionary adaptations.

This study identifies Alexidine dihydrochloride as a broad-spectrum antifungal drug effective against multiple fungal pathogens and preformed biofilms.

This paper confirms Methanosarcina barkeri can uptake electrons from cathodes, linking it to increased methane production and identifying both hydrogenase-mediated and hydrogenase-independent pathways for cathodic electron uptake.