Y. Ding

This paper surveys the current state of root phenotyping, identifying key trends, challenges, and needs in the field.

This study shows Harringtonine inhibits SARS-CoV-2 membrane fusion by targeting both the viral S protein and host TMPRSS2, effectively blocking infection in delta and Omicron variants.

This study maps 3D genome reorganization during skeletal muscle stem cell activation, proliferation, and aging using Hi-C, revealing how chromatin architecture influences gene expression and lineage progression.

The paper identifies a conserved CTL epitope in the SARS-CoV-2 spike protein that is compatible with most HLA alleles and suitable for evaluating CD8+ T cell responses.

The paper develops a causal framework to identify tumor-specific intercellular communication networks in head and neck squamous cell carcinoma, revealing subtype-specific patterns linked to clinical outcomes.

The paper identifies an additional signal in bacterial outer membrane proteins that enhances assembly efficiency and maintains membrane integrity through interaction with BamD.

This study profiles flavone accumulation in seven Scutellaria species, revealing organ-specific patterns and identifying a rare 4-hydroxyflavone isomer in some species.

This study shows that deleting STAT3 in stromal cells prevents kidney fibrosis by blocking pericyte trans-differentiation and migration.

This study compares a wild-type SARS-CoV-2 spike protein DNA vaccine with an optimized sequence in a mouse model, showing enhanced immune responses and protection against viral challenge.

The paper examines S. commune fruiting bodies and hyphae to confirm the presence of calcium oxalate crystallites, demonstrating biomineralization in this fungus.

This study identifies ERAD as a proteostasis checkpoint during β-selection, showing Sel1l deficiency causes ER stress and apoptosis, impairing β T cell development.

This study develops a novel ECG monitoring system for zebrafish to assess cardiovascular function and drug effects, showing improved efficiency and reduced side effects.

This study evaluates a rapid whole blood test for measuring SARS-CoV-2 Spike-specific T cell responses in vaccinated and infected individuals, finding a wide dynamic range independent of neutralizing antibodies.

This study investigates how temperature affects cardiac remodeling in rainbow trout, finding sex-specific changes in MAPK phosphorylation during cold and warm acclimation.

This study shows KSHV infection of MSCs drives MEndT to generate hybrid M/E state cells, which are tumorigenic and recapitulate KS features, with vFLIP as a key regulator.

The paper investigates embryo-endosperm signaling in rice using a mutant to identify regulatory pathways affecting endosperm development and proposes a new staging system for rice seed development.

This study shows KSHV resolves the bivalent chromatin of PROX1 to activate its expression, promoting MEndT and tumorigenic features in MSCs.

The paper demonstrates that focused ultrasound activation of the hepatic neural plexus restores glucose homeostasis in diabetes models across multiple species.

This study shows that viral proteins interact combinatorially, leading to new biological functions beyond their individual roles during infection.

This study identifies and validates SARS-CoV-2 CD8+ T cell epitopes, demonstrates their cross-presentation, and shows the efficacy of peptide vaccines in transgenic mice.

SongExplorer uses deep learning to discover, annotate, and segment animal acoustic signals with higher accuracy than existing methods and comparable to human experts.

The paper identifies two highly conserved druggable sites in the SARS-CoV-2 replication-transcription complex as potential targets for broad-spectrum antiviral drugs.

This study uses silver-stained micro-CT to quantitatively analyze melanin distribution in zebrafish larvae, enabling detailed whole-body phenotyping of pigment patterns and mutant phenotypes.

This study analyzes MDR E. coli from human gut microbiota, revealing high diversity, virulence gene variation, and potential transmission from raw meat.

This paper introduces a deep learning method to improve light-field microscopy, enabling high-speed, artifact-free volumetric imaging of biological processes.

This study uses computational fluid dynamics to model microvascular changes in zebrafish tail regeneration, showing dynamic shifts in wall shear stress and flow rate during vascular remodeling.

The paper shows that inhibiting HSP90 reduces STAT3-mediated muscle wasting in cancer cachexia by disrupting the HSP90/STAT3/FOXO1 axis.

The paper shows that CSP reduces ATG levels via ubiquitination by NEDD4, enabling EEFs to evade IFN-gamma-mediated killing in hepatocytes.

This study investigates the role of the abaI/abaR quorum sensing system in Acinetobacter baumannii virulence, showing its impact on growth, biofilm formation, antimicrobial susceptibility, and gene expression.

This study identifies a mixture of polysaccharides from Ecklonia kurome that inhibit SARS-CoV-2 by targeting multiple viral proteins, with the cocktail-like effect enhancing antiviral activity.