B. Yao

Label-Free Electrochemical Imaging of Single Extracellular Vesicles

This paper introduces a label-free technique to quantify single extracellular vesicles by measuring their electrochemical impedance, enabling differentiation between cancerous and healthy cell-derived vesicles.

Characterization of the SARS-CoV-2 BA.5 Variants in H11-K18-hACE2 Hamsters

This study characterizes SARS-CoV-2 BA.5 variants in H11-K18 hACE2 golden hamsters, showing disease progression and severity similar to human infections, supporting the model's utility for research.

The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops

The paper identifies DDX1 as an interactor of the RNA exosome subunit EXOSC3 and shows that their interaction is reduced during DNA damage, affecting R-loop levels in neuronal cells.

Genomic insights into the phylogeny and biomass-degrading enzymes of rumen ciliates

The paper presents 52 high-quality genomes of rumen ciliates, reclassifying them into 19 species and identifying their biomass-degrading enzymes.

Ratiometric 4Pi single molecule localization with optimal resolution and color assignment

This paper introduces a ratiometric multi-color imaging strategy for 4Pi-SMLM that achieves optimal 3D resolution and color separation with minimal loss of localization precision.

PD-L1 lncRNA splice promotes lung adenocarcinoma progression via enhancing c-Myc activity

The paper identifies PD-L1-lncRNA, a long non-coding RNA splice variant of PD-L1, that promotes lung adenocarcinoma progression by enhancing c-Myc activity.

Characterizing Activity and Thermostability of GH5 Cellulase Chimeras from Mesophilic and Thermophilic Parents

This study creates GH5 cellulase hybrids from mesophilic and thermophilic parents to identify elements enhancing thermostability, finding improved thermal properties in some hybrids.

Lung Cancer Explorer (LCE): an open web portal to explore gene expression and clinical associations in lung cancer

The paper constructs a lung cancer database with gene expression and clinical data from 6,700 patients and develops an open web portal for data exploration and analysis.