L. Xu

The paper characterizes the complete genome of a novel coronavirus, WHCV, linked to a respiratory outbreak in Wuhan, finding it closely related to SARS-like bat coronaviruses.

This study examines how social support moderates the relationship between role conflicts and job satisfaction among nurses with multiple roles in China.

This study identifies TP63, SOX2, and KLF5 as core regulatory circuitry transcription factors in ESCC that drive epigenetic modifications and tumor growth through super-enhancer interactions.

The paper identifies a novel rpoB mutation in MRSA associated with tedizolid resistance and reports cross-resistance to other antibiotics.

This study shows gut bacteria enhance dsRNA-induced mortality in leaf beetles by accelerating dsRNA degradation and causing microbiota dysbiosis.

This study identifies HDAC6 as a driver of RMS tumor growth, self-renewal, and migration/invasion, with RAC1 as a key mediator, suggesting targeting the HDAC6-RAC1 axis as a therapeutic strategy.

This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.

This study shows that longer double-stranded RNAs accumulate more in plastids, leading to stronger RNAi effects against Colorado potato beetle larvae.

The paper introduces a method to predict the functionality of low-frequency missense mutations by integrating mutation counts with relative mutational difficulty, revealing functional p53 mutations and potential cancer prevention strategies.

This study evaluates a novel Brucella multiepitope recombinant protein as a diagnostic antigen for brucellosis, showing strong immunoreactivity and diagnostic accuracy in mice.

This study identifies Sle1 as a key factor in β-lactam resistance in MRSA USA300, showing that high Sle1 levels promote cell separation and reduce oxacillin sensitivity.

The paper shows MSI-1 and EXC-7 regulate serotonin-mediated mating behaviors in C. elegans by stabilizing mRNA of a G protein and affecting serotonin synthase activity.

The paper identifies collagen production as an adaptation strategy in acidotic cancer cells, showing correlation with patient survival.

The paper identifies 14 genes transposed from Z to W chromosomes in songbirds within 9 million years, showing that sex-specific and dosage selections help restore genes on degenerating W chromosomes.

This study investigates the evolutionary dynamics of sex chromosomes in paleognathous birds, finding that large non-degenerate regions are retained and that evolutionary rates vary across different genomic regions.

This study evaluates the efficacy and adverse effects of antibiotics in treating M. abscessus pulmonary disease, finding that four antibiotics correlate with treatment success but are associated with severe side effects.

This study identifies IbaG, a BolA-like protein in V. cholerae, as critical for cell shape and envelope integrity through its role in iron-sulfur cluster protein biogenesis.

This study shows that the I232T SNP in FcγRIIB causes structural changes that reduce ligand binding, contributing to SLE pathogenesis.

This study shows that E. coli lifespan follows the Gompertz law of mortality, with ageing rate modulated by maintenance investment in response to environmental constraints.

This study uses single-molecule long-read sequencing to analyze red clover transcriptome, identifying novel splice isoforms, alternative splicing events, and non-coding RNAs.

This study identifies ANRIL as a key lncRNA promoting HTLV-1-induced ATL cell proliferation through interaction with EZH2 and activation of NF-κB.