Q. Qi

Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection

This study evaluates hybrid immunity against the Omicron variant JN.1 11 months after breakthrough infection, showing heterogeneous responses and increased neutralization following reinfection.

Ferroptosis induced by phenolic compound-iron complex

This study shows phenolic compounds induce ferroptosis via iron complex formation, leading to cell death in bacteria and mammals, with potential therapeutic and biotechnological applications.

Remodeling the central metabolism of Escherichia coli enables a universal chassis

This paper describes the construction of an E. coli strain with suppressed overflow metabolism, leading to improved chemical and protein production.

Uncovering Bacterial Hosts of Class 1 Integrons in an Urban Coastal Aquatic Environment with a Single-Cell Fusion-Polymerase Chain Reaction Technology

The paper develops a modified epicPCR method to identify bacterial hosts of class 1 integrons in polluted coastal waters, revealing Rhizobacter as a novel host.

Microbiota-stimulated Interleukin-22 regulates brain neurons and protects against stress-induced anxiety

This study identifies IL-22 as a key immune-to-brain signal that reduces stress-induced anxiety by acting on septal neurons.

A rapid alkalinization factor-like peptide EaF82 impairs tapetum degeneration during pollen development through induced ATP deficiency

The paper identifies EaF82, a RALF-like peptide, which delays tapetum degeneration in Arabidopsis by reducing ATP levels through AKIN10 interaction, impairing pollen development.

Comprehensive dissection of immune microenvironment in the progression of early gastric cancer at spatial and single-cell resolution

This study uses spatial transcriptomics and single-cell RNA-seq to analyze immune microenvironment changes in gastric cancer progression, identifying immune cell dysregulation and key signaling pathways.

Discovery of integrons in Archaea: platforms for cross-domain gene transfer

The paper identifies integrons in Archaea and demonstrates their role in facilitating horizontal gene transfer between Archaea and Bacteria.

Methods for the targeted sequencing and analysis of integrons and their gene cassettes from complex microbial communities

This paper presents standardized methods for PCR amplification, sequencing, and validation of integron gene cassettes from complex microbial communities, demonstrating their ability to recover diverse functional elements including antibiotic resistance genes.

SIRT2-knockdown Rescues GARS-induced Charcot-Marie-Tooth Neuropathy

This study shows that reducing SIRT2 rescues GARS-induced neuropathy in a Drosophila model by restoring acetylated tubulin levels and axonal transport.