R. Zhang

This study identifies ACE2 orthologs from diverse species that can support SARS-CoV-2 entry, suggesting a broad host range for the virus.

This study uses human liver organoids to show SARS-CoV-2 infects cholangiocytes, disrupts bile transport, and causes liver damage, suggesting targeting viral effects on the liver could improve COVID-19 treatment.

This study identifies and characterizes ZmCPAs in maize, showing their roles in salt tolerance through expression analysis and functional validation.

This study identifies MBOAT7-driven phosphatidylinositol remodeling as a driver of clear cell renal cell carcinoma progression and highlights MBOAT7 as a potential therapeutic target.

This study identifies sPML-II as the isoform that inhibits PRV infection by suppressing viral gene transcription through its 7b region.

This study shows MBOAT7 regulates glycolysis in ccRCC by reducing glycolytic gene expression, intermediates, and respiration, and improving survival in xenograft models.

The paper introduces a microtubule probe that enables correlative super-resolution fluorescence and electron microscopy to study microtubule ultrastructure.

The paper identifies and characterizes three shared enzymes in mitochondrial and plastidial fatty acid synthase systems and shows their dual localization and functional consequences.

This study shows that GIT1 and β-Pix form a condensed enzyme complex via phase separation, enabling compartmentalized signaling in different cellular contexts.

This study isolates and characterizes ten novel pelagiphages infecting Pelagibacter strains, revealing their genetic diversity, global distribution, and ecological significance.

This study identifies riboflavin as a direct mediator of electron transfer in microbial P450 monooxygenase dealkylation, revealing a novel mechanism involving FAD/FMN cofactors.

This study found that a significant proportion of E. coli isolates from ready-to-eat lettuce in Northern California carry beta-lactam resistance genes, posing a potential risk for human infections.

This study investigates how Chlamydomonas sp. UWO241 maintains high cyclic electron flow and rewired metabolism under high salinity stress.

This study shows that rabies virus glycoprotein suppresses gastric cancer migration by inhibiting the 7-nAChR-MEK/ERK-EMT pathway.

This study identifies MnJ, a colloidal manganese salt, as a potent universal adjuvant that induces both humoral and cellular immune responses, including CTL activation and mucosal immunity.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This paper introduces two 2D HETCOR NMR pulse sequences to enhance sensitivity for rigid and mobile components in heterogeneous systems by leveraging different MAS conditions and polarization transfer mechanisms.

This study shows that Dram1 deficiency in zebrafish increases susceptibility to Mycobacterium marinum infection by impairing phagosome maturation and inducing pyroptotic cell death in macrophages.

This paper identifies carbon starvation stress as a trigger for the PprB regulon in Pseudomonas aeruginosa, revealing its role in enhancing biofilm adhesion through BapA and CupE.

The paper reanalyzes biophysical and structural data to correct the previous claim that Pac13 is a monomer, showing it is actually a homodimer.

This study uses cryo-EM and molecular dynamics to show that α-tubulin acetylation at K40 reduces loop disorder and may affect microtubule stability.

This study identifies 11 new pelagiphages in the Podoviridae family that integrate into host SAR11 genomes, providing evidence of both lytic and lysogenic infection mechanisms.

This study shows that Optineurin and p62 are required for autophagic host defense against mycobacterial infection in zebrafish.

This study shows Bclaf1 is degraded by alphaherpesvirus US3 and is critical for type I interferon signaling and antiviral immunity.

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.

This study identifies clofazimine as a Cx46 inhibitor that targets glioblastoma cancer stem cells by disrupting gap junction communication, enhancing the efficacy of temozolomide.

The paper identifies structural capacitance as a new mechanism in protein evolution that generates microstructure in disordered regions, linking it to disease and evolutionary adaptability.