Y. Wu

This study isolates and characterizes two mesenchymal stem cell lines from a neonatal common hippo, showing their fibroblastoid morphology, normal karyotype, and stemness markers, with distinct differentiation potentials.

This study identifies a resident state in influenza polymerase that enables smooth transitions between transcription and replication cycles through structural analysis.

This study identifies Nrf2/FAM134B-mediated ER-phagy as a protective mechanism against oxidative damage in intervertebral disc degeneration.

The paper applies deep learning to identify anther dehiscence states in cotton to screen for heat-tolerant varieties and support genetic breeding research.

This study develops engineered small extracellular vesicles targeting FGL1 and PD-L1 to suppress immune rejection in transplantation by inhibiting T cell activation and improving graft survival.

The paper introduces a cost-effective flat-field illumination module for TIRF-based super-resolution microscopy to address uneven illumination issues.

This study identifies SHIP164 as a lipid transport protein that facilitates bulk lipid transfer at the endosome-Golgi interface, affecting membrane traffic and organelle movement.

The paper introduces Yn situ, a single RNA molecule in situ detection method, showing it is sensitive and quantitative for gene expression in mouse olfactory epithelia.

This study shows that CD47 cross-dressing via extracellular vesicles inhibits phagocytosis without causing cell death, offering a safer alternative to CD47 overexpression.

This study identifies CsMYB4a as a multifunctional transcription factor that regulates the auxin signaling pathway and phenylpropane/lignin pathways in Camellia sinensis.

The paper shows that RZ-1 and PRC2 work together to silence NCED6, a gene involved in ABA biosynthesis, which is essential for seed germination in Arabidopsis.

This study shows SARS-CoV-2 indirectly causes BBB injury and neuroinflammation through systemic inflammation, not direct viral infection, using a linked alveolus-BBB organ chip platform.

The paper develops a computational model of cell growth and proteome increase to explain the correlation between cell and nuclear volume, showing that transport rates and ribosome dynamics influence growth and volume ratios.

This study shows HSV-1 infection releases cGAS from chromatin into the nucleus, where it senses viral DNA and activates type I IFN production.

This study identifies CaMYB101 as an anthocyanin biosynthesis repressor in pepper through genome-wide R2R3-MYB analysis and virus-induced gene silencing.

This study shows that noradrenaline and ATP regulate adiponectin exocytosis in white adipocytes, and their signaling is disrupted in obesity-associated diabetes.

This study shows that OsLEC1 inhibits photosynthesis in rice embryos to promote seed dormancy by regulating hormonal pathways and gene networks.

The paper engineers a DNAJB1-PRKACA fusion in HEK293T cells to study its oncogenic effects, finding LINC00473 overexpression dependent on PKA signaling.

This study shows ASH1L's enzymatic activity is essential for MLL-AF9-induced leukemogenesis by enhancing target gene expression through histone modification.

This study uses TMT-based proteomics to analyze the antibacterial effects of YACTH against Staphylococcus aureus, identifying 490 differentially expressed proteins and their biological pathways.

This study investigates the distribution and molecular evolution of the AcrIF7 anti-CRISPR family, identifying sub-clusters, variants, and functional residues.

This study shows that (R)-NNAL promotes lung cancer progression by deactivating LKB1 through β-AR signaling, while (S)-NNAL has weaker effects.

This study shows that caveolae regulate oxidative stress response by lipid peroxidation, CAVIN1 release, and NRF2 interaction, affecting cell death and regeneration.

This paper applies RCAN to enhance fluorescence microscopy image volumes, achieving denoising and resolution improvements across multiple microscopy techniques.

This paper introduces a multiview super-resolution microscopy approach that enhances confocal microscopy resolution and reduces phototoxicity across multiple scales.

This study shows a single-dose AAV-based vaccine induces long-lasting neutralizing antibodies against multiple SARS-CoV-2 variants in rhesus macaques.

This study quantifies the mechanical behavior of vertebral endplates and finds that bone volume fraction and bone mineral density predict many mechanical properties, while tissue-level density measurements do not.

This study develops glycan-modified SARS-CoV-2 nanoparticle vaccines that induce potent neutralizing antibodies and single-dose protection against SARS-CoV-2 in multiple animal models.

This study uses herbarium records and climate data to show that Lythrum salicaria evolved parallel phenology clines across North America over 150 years, followed by microevolutionary stasis.